"Tumor antigens" refers to proteins or molecules present on the surface of cancer cells. These antigens are recognized by our immune system, which then triggers an immune response to fight against the cancer cells. Full definition
In a 2009 paper published in Nature Materials, Mooney demonstrated that this could be achieved by loading a porous scaffold — about the size of a dime — with tumor antigen as well as a combination of biological and chemical components meant to attract and activate dendritic cells. (sciencedaily.com)
The team also created an ImmunoMap of the diversity of T - cell receptors specific for tumor antigens in mice with and without tumors. (sciencedaily.com)
Principal Investigator John Morris, MD, clinical co-leader of the Molecular Therapeutics and Diagnosis Program for the CCC, co-leader of the UC Cancer Institute's Comprehensive Lung Cancer Program, professor in the division of hematology oncology at the UC College of Medicine and UC Health medical oncologist, says a number of antitumor vaccines have shown promise for causing immune responses against tumor antigens to improve patient outcomes. (sciencedaily.com)