We also found that cells derived from this novel subpopulation form colonies readily, are highly tumorigenic in immune - deficient mice, and exhibit both stem - like and EMT phenotypes. (breast-cancer-research.biomedcentral.com)
FDA's position on assessment of tumorigenic potential of cell products for regenerative medicine (stemcellassays.com)
Our previous work has shown that the CD44 + and CD44 + α2β1 + prostate cancer cell populations are enriched in tumorigenic and metastatic CSCs, whereas the α2β1 + prostate cancer cells most likely mark fast - proliferating tumor progenitors (28, 29). (cancerres.aacrjournals.org)