"Tumour initiation" refers to the process by which a normal cell in the body begins to divide and grow uncontrollably, leading to the formation of a tumour. It is the first step in the development of cancer. Full definition
Using a CRISPR - dCas9 epigenetic editing tool, the researchers methylated different genes in healthy breast cells and found that those changes were sufficient to cause the cells to undergo «hyperproliferation» — abnormally rapid cell division which is an early stage of tumour initiation. (sciencedaily.com)
The direct application of physics, engineering, chemical or mathematical concepts to address the underlying physical processes of cancer, including tumour initiation, growth and metastasis. (cancerresearchuk.org)