It has been observed in this pathway that a single - base missense transversion causes the replacement of valine with glutamic acid at amino acid residue 600 in BRAF that is detected in about 85 % of nevi and melanoma [32, 33]. (jbiomed.com)
Valine in particular helps to stop muscles from breaking down during periods of strenuous exercise. (aminoacidstudies.org)
For instance, the amino acid valine was altered to isoleucine at position 223. (sciencenews.org)