Phrases with «xenograft models»

Xenograft models refer to a type of scientific experiment where human cells or tissues are implanted into different species of animals, usually mice. This helps researchers study and understand the behavior of human diseases and test potential treatments before trying them on humans. Full definition

Sentences with «xenograft models»

  • Liu JF, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, Zervantonakis IK, Selfors LM, Shen Y, Pritchard CC, Zheng M, Adleff V, Papp E, Piao H, Novak M, Fotheringham S, Wulf G, English J, Kirschmeier PT, Velculescu VE, Paweletz CP, Mills GB, Livingston DM, Brugge JS, Matulonis UA, Drapkin R.: Establishment of patient - derived tumor xenograft models of epithelial ovarian cancer for pre-clinical evaluation of novel therapeutics. (pennmedicine.org)
  • Terbinafine, a U.S. Food and Drug Administration — approved antifungal drug targeting SQLE, markedly inhibited SQLE - induced NAFLD - HCC cell growth in NAFLD - HCC and HCC cells and attenuated tumor development in xenograft models and in Sqle transgenic mice. (stm.sciencemag.org)
  • A quartet of samples were sequenced in this study — the primary breast tumor, the matched normal tissue, the brain metastasis (from which the patient died), and finally, a mouse xenograft model developed in «humanized» NODSCID mice. (massgenomics.org)
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