At the same time, Dr. Gitler's lab found that Dbr1 suppressed TDP - 43 toxicity in yeast models. (gladstone.org)
Eventually, using yeast models, the target of rapamycin (TOR) was identified, and the human counterpart was soon discovered — hence the name mammalian TOR, now given the catchy moniker — mTOR. (idmprogram.com)
Using florescent tagging, they tracked the enzyme's presence on yeast models — which offer a number of commonalities in the processes of meiosis in humans. (sciencedaily.com)