Regardless of the inciting cause, pancreatitis stems from the premature activation of trypsin within the acinar cells which leads to the activation of other zymogens. (veteccsmalltalk.com)
«The major digestive enzymes exist in pancreatic acinar cells in inactive forms called zymogens. (nextgendog.com)
Facilitating the proximity of CED - 3 zymogen molecules was found to induce caspase activation and cell death. (science.sciencemag.org)