The word "irreparable" means something that cannot be fixed or repaired. It describes a situation or damage that is permanent and cannot be undone. Full definition
The power once bestowed on each artifact is strong, and capable of causing irreparable harm, should they fall into the hands of the evil. (gamebra.com)
Scotland's local government body Cosla has raised concerns that the government's «hasty» changes to the country's education system «could do irreparable damage for future generations». (educationbusinessuk.net)
Beyond choking, some common small items like the silver button batteries inside remote controls are toxic and can cause irreparable harm if swallowed. (babycenter.com)