Patients with a rare genetic disease known as junctional epidermolysis bullosa (JEB) suffer from just this painful phenomenon. (closerlookatstemcells.org)
Immunolocalization of intergrin alpha 6 beta 4 in mouse junctional epithelium suggests an anchoring function to both the internal and the external basal lamina. (vicc.org)
Their young patient had a severe form of the disease known as junctional EB, caused by a mutation in a gene encoding part of the protein laminin 332, which makes up a thin membrane just below the epidermis. (sciencemag.org)