He began by using an electric current to open holes in the bacteria's cell walls. (discovermagazine.com)
Our offensive line strengths are opening holes for running backs, and protecting long enough to get the ball out for a screen and then blocking down field. (testudotimes.com)
Some of them have open holes at their tops and bottoms and are stacked more or less like concrete sewer pipes. (scientificamerican.com)