The phrase "significant blow" means a strong and impactful hit or challenge that has a major effect on a person, situation, or outcome. Full definition
There has been a slew of bad news over the past month for the leading daily fantasy sports companies, but the latest may be the most significant blow so far. (fortune.com)
The much - touted Nigerian e-commerce sector took two significant blows early in 2018, both of which raise serious questions about the... (disrupt-africa.com)
The Accord and Mazda 6 are class standouts in terms of athleticism and engineering prowess, but the Sonata Sport isn't far behind, and its value quotient and interior space land significant blows against those two big competitors. (speedsportlife.com)