However, in the absence of substantial effects on teacher - ratings, we can not ascertain effects are due to specific treatment procedures. (link.springer.com)
Already there are numerous indications of substantial effects in response to warming of the past few decades. (journals.plos.org)
Environmental risk factors for ADHD have shown to have more substantial effect sizes than genetic factors [27], and may have more immediate relevance for clinical treatment. (link.springer.com)