«We have been extremely conservative in not reporting back variants» of uncertain significance, she said. (sciencemag.org)
However, when specifically asked about a variety of possible incidental findings, only 57 % wanted to know if they were found to have a gene variant that would cause an unpreventable and serious illness, and only 47 % wanted to know about a gene variant of uncertain significance. (sciencedaily.com)
Genetic testing labs, including Myriad, normally provide clients with information on gene variants that are known to increase the risk of disease (pathogenic), likely to be pathogenic, or of uncertain significance. (sciencemag.org)