Not exact matches
To test the hypothesis that exercise could increase brain progranulin levels in Grn
+ / −
mice, we solo - housed 6 - month - old wild - type (Grn
+ /
+), Grn
+ / −, and Grn − / −
mice in standard
mouse cages or cages with running
wheels for 7.5 weeks.
We therefore tested 4 - to 8 - month - old Grn
+ / −
mice with 4 weeks of
wheel running (Fig. 4A), a time period that was previously reported to increase progranulin in wild - type
mice (Asakura et al., 2011).
Wheel running for 7.5 weeks did not significantly increase any measure of progranulin in wild - type or Grn
+ / −
mice.
When the result is not so obvious, you can simply measure using the crosshair in MT4 (click the
mouse wheel or Ctrl
+ F).
Zooming: To zoom in and out of the map, scroll up and down with your
mouse wheel while you
mouse over the interactive map or click on the
+ and - buttons respectively.
In addition to a left button, a right button and a clickable scroll
wheel, the
mouse sports two dots - per - inch (DPI) sensitivity buttons next to the right button, two programmable buttons next to the left button, two thumb buttons and an Easy - Shift [
+] button on the thumb rest, which lets users access a second set of button commands.