Sentences with phrase «-lcb- kappa»

Does a decline in the number of Phi Beta Kappas going into the ministry reflect a decline in quality?

In animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be shown to get reduced following consumption of either sweet potato or its color - containing extracts.

UltranorTM HCF is the first commercially available, enriched beta and kappa casein milk protein fraction.

Caseins include alpha - casein, beta - casein, kappa - casein and gamma - casein.

Cohen's kappa was used to determine agreement between HSR (products that scored 3 stars or more) and NPSC (products that met NPSC).

Add the tapioca flour and kappa carrageenan.

its always going to be blue and white, far better than the londsdale one and kappa versions years ago, at least umbro play it safe, collar looks good, all we need is a sponsor!!!

To me it looks like a Warrington wolves rlfc kit i do nt like kappa at all to much branding all over the shirt as well as it looks like a rugby shirt but it is one of the best leeds away kits in years.

Jenifer Rajkumar is an Ivy - league educated UPenn (phi beta kappa) and Stanford Law School (summa cum laude) graduate, a civil rights attorney and the elected Downtown District Leader.

When kappa - carrageenan is mixed with clay - based nanoparticles, injectable gelatin is obtained.

The study uses a commonly used thickening agent known as kappa - carrageenan, obtained from seaweed, to design injectable hydrogels.

Most of the commonly occurring cancers, notably breast, prostate, and lung cancer, spread (metastasize) to bone; I was set to the task of studying the role of a transcription factor (gene - expression regulator), NF B (nuclear factor kappa B), in cancer metastasis.

«These effects were reduced, however, in terms of both intensity and duration, if the mice had been treated with a kappa - opioid receptor antagonist, a drug that blocks the activity of one of the brain's own opioid systems.»

Since genes for the T - cell receptor beta chain were previously shown to be on mouse chromosome 6, all three of the Ig - like multigene families expressed and rearranged in T cells are located on different chromosomes, just as are the B - cell multigene families for the Ig heavy chain, and the Ig kappa and lambda light chains.

Bohn noted isoquinolinone 2.1 is one example of a new class of «biased» kappa agonists that avoid many central nervous system side effects by preferentially activating a G protein - mediated signaling cascade without involving another system based on β - arrestin protein interactions.

Researchers have determined how morphine derivatives bind to the kappa opioid receptor, which should enable safer painkillers to be developed

DNA elements are asymmetrically joined during the site - specific recombination of kappa immunoglobulin genes

For example, nuclear factor - kappa B (NF - kB) is a complex of proteins that acts as a master switch for turning inflammation genes on and for controlling cell death.

Working with cultures of respiratory tract cells, Elias's team found that the gene that codes for il - 6 is inactive unless a protein known as nf - kb (nuclear factor - kappa beta) attaches to the gene.

In the fetal liver hybridomas, which were constructed from fetal liver cells and a tumor cell, no light chain gene rearrangement was observed, whereas in the 70Z / 3 cell line a kappa light chain rearrangement probably occurred.

Not only did the CLA's impact on NF - kappa - B activity reduce the production of the COX - 2 enzyme, but it also dampened the activity of any COX - 2 that was made.

They found that it modulated the activity of a molecule, NF - kappa - B, that controls parts of the immune response.

The sequence of the complementary DNA encoding pp40 revealed similarity to the gene encoding MAD - 3, a protein with mammalian I kappa B - like activity.

«But when kappa opioid receptors are activated, this glutamate release associated with «safety» was tamped down.

Their new approach also reduces the potential for drug abuse and avoids the most common side effects — sedation and anxiety — of drugs designed to target the nervous system's kappa opioid receptors (KORs).

Humans also have kappa opioid receptors that work in the same way.

«How kappa opioid receptors drive anxiety.»

University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety.

Using X-ray crystallography and computer modelling, Daniel Wacker at the University of North Carolina and his colleagues have designed a new opioid molecule that binds tightly and exclusively to kappa receptors, potentially minimising the likelihood of addiction or side effects.

As a monomer, GR represses the activities of pro-inflammatory transcription factors, such as activator protein 1 or nuclear factor kappa B (NF - kB) by a tethering mechanism called transrepression.

Opioids can also work by binding to kappa receptors, a route to less pain that doesn't seem to trigger addiction.

Unlike SSRIs which target the serotonin system in the brain, BU10119 works by blocking receptors called kappa opioid receptors.

The average inter-observer agreement was kappa = 0.78 and the average intra-observer agreement was kappa = 0.72.

Dr. Carlezon and his group were the first to report that a class of drugs called kappa - opioid receptor (KOR) antagonists has antidepressant, anti-anxiety, and anti-stress effects in their behavioral tests.

The kappa receptors are less involved with addiction than mu, though kappa - based drugs can cause emotional distress and hallucinations.

Those naturally produced opioids, and the opioid drugs that imitate them, inhibit pain by acting on three kinds of opioid receptors — mu, kappa and delta — that are found on the outside of nerve cells in the brain, spinal cord, digestive tract and elsewhere.

Dr. Chartoff also studies the mechanisms by which kappa - opioid receptor systems modulate cocaine reward and the depressive - like states induced by cocaine withdrawal.

Blockade of kappa - opioid receptors attenuates the development of depressive - like behaviors induced by cocaine withdrawal in rats.

Ablation of kappa - opioid receptors from brain dopamine neurons has anxiolytic - like effects and enhances cocaine - induced plasticity.

This has important ramifications for the neural mechanisms underlying mood and affect as well as for the contribution of kappa receptors to addictive behavior in men versus women.

They have demonstrated that female rats are less sensitive than males to the depressive - like effects of kappa - opioid receptor activation.

A key finding from these studies is that kappa - opioid receptor activation is necessary for binge cocaine - induced, depressive - like states in rats.

Sex differences in sensitivity to the depressive - like effects of the kappa opioid receptor agonist U-50488 in rats.

Within this context, there are two primary lines of research in the lab, sex differences in addiction and the role of kappa - opioid receptors in cocaine withdrawal.

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF -[kappa] B signalling.

HYPERTONIC SALINE ATTENUATES TNF -[alpha]- INDUCED NF -[kappa] B ACTIVATION IN PULMONARY EPITHELIAL CELLS.

Nuclear factor kappa B in the dorsal raphe of macaques: an anatomical link for steroids, cytokines and serotonin.

Nuclear factor kappa - B mediates selective induction of neuronal nitric oxide synthase in astrocytes during low - level inflammatory stimulation with MPTP.

Inhibits the activity of dimeric NF - kappa - B / REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals.

Hepatitis C Virus Regulates Transforming Growth Factor [beta] 1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor [kappa] B - Dependent Manner.