Sentences with phrase «.7 sodium channel»

Mutations in the human gene encoding the Nav1.7 sodium channel can lead to either the inability to sense pain or pain hypersensitivity.

The team first tested the antibody in cultured cells engineered to express the Nav1.7 sodium channel.

Not exact matches

The company's therapeutic candidates are highly selective sodium ion channel 1.7 (Naᵥ1.7) inhibitors based on naturally occurring small molecules.

One particular type of sodium channel, called the Nav1.7 subtype, is responsible for sensing pain.

Genetic studies in humans have recently identified a mutation in the voltage-gated sodium (Nav) channel, Nav1.7, which causes people to lose the ability to feel pain.

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.