By comparing the behavior of XBP -
1s in the obese mice with that in lean, healthy ones, he discovered an inflammatory protein that modifies XBP - 1s in healthy animals so it can be shuttled into the nucleus.
Not exact matches
Ozcan realized that inflammation might help when he noticed that
in obese diabetic
mice, XBP -
1s failed to enter the cell nucleus, where insulin function is regulated.
A new thiazolidinedione, NC - 2
100, which is a weak PPAR - γ activator, exhibits potent antidiabetic effects and induces uncoupling protein
1 in white adipose tissue of KKAy
obese mice.
Calorie Restriction - like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile
in Obese Humans Cell Metabolism 20
11 (Nov 2);
14 (5): 6
12 — 622 ~ FULL TEXT The result of just 30 days on resveratrol were impressive: (
1) The same gene regulators (AMPK, SIRT
1 and PGC -
1a) were activated
in this study as are activated by caloric restriction and resveratrol
in mice and endurance training
in humans.