Whether this system can be applied to monitoring and analysis of
3D cell differentiation remains to be studied.
Not exact matches
This is the first time we've observed how matrix stress relaxation impacts stem
cell differentiation in
3D.»
The osteogenic
differentiation of adipose tissue - derived precursor
cells in a
3D scaffold / matrix environment.
Based on previous protocols [5, 6] they have now created a
3D protocol for chondrogenic lineage
differentiation via the generation of a putative chondrogenic progenitor
cell population, and have found that using this protocol C - iPSCs can be readily differentiated into cartilage in a manner comparable to that of mature chondrocytes [7].
However, researchers from the laboratory of Nenad Bursac (Duke University, Durham, NC, USA) have recently described the production and
differentiation of induced myogenic progenitor
cells (iMPCs) from hPSCs into the first entirely hPSC - derived
3D muscle tissues that survive, vascularize, and maintain function following transplantation [5].
We have previously reported that these KD
cells are partially transformed as evidenced by the disruption of epithelial polarity and morphological
differentiation in the
3D IrECM (He et al., 2008).