Sentences with phrase «3d microenvironment»
Development and validation of a modular 3D microenvironment platform technology for studying prostate cancer - induced bone metastasis.
http://additivebiomanufacturing.org/
Review of «Evaluating Interaction of Cord Blood Hematopoietic Stem Progenitor Cells with Functionally Integrated 3D microenvironments» from STEM CELLS Translational Medicine by Stuart P. Atkinson
The Chips are cultured under continuous flow within engineered 3D microenvironments that go beyond conventional 3D in vitro models by recapitulating in vivo intercellular interactions, spatiotemporal gradients, vascular perfusion, and mechanical forces — all key drivers of cell architecture, differentiated function, and gene expression.
Not exact matches
«Because the primary Small Intestine Chip recapitulates the physical microenvironment that cells experience inside the human body, such as fluid flow and cyclic peristalsis - like stretching motions, it exhibits a genome - wide gene expression profile that comes closer to its in vivo counterpart than that of the same intestinal cells grown as 3D organoids,» said first - author Magdalena Kasendra, Ph.D., a former Postdoctoral Fellow on Ingber's team and now Principal Scientist at Emulate, Inc. in Boston.
Presumably, a scaffold provides some sort of microenvironment — a niche that allows a cell to adopt the normal 3D morphology that it would have in the body.
In the current study, the authors used single - cell RNA sequencing (RNA - Seq) to monitor how individual cells change when they are combined in a three - dimensional (3D) microenvironment.
Modeling multiple myeloma - bone marrow interactions and response to drugs in a 3D surrogate microenvironment
3D bioengineered model of the tumor - stroma microenvironment of late stage ovarian cancer.
Microphysiological systems (MPSs) are in vitro models that capture facets of in vivo organ function through use of specialized culture microenvironments, including 3D matrices and microperfusion.
«3D Microfluidic Models of the Vascularized Tumor Microenvironment: Advancing Precision Medicine and Understanding Collective Migration»