Sentences with phrase «3t3 fibroblast cells»

This microscopic image of fibroblast cells shows the induction of cell fusion by a newly described gene and its protein, called myomerger.

A team led by Byeong - Chun Lee of Seoul National University in South Korea created the dogs by cloning fibroblast cells that express a red fluorescent gene produced by sea anemones.

Lee's team used a retrovirus to transfer the fluorescent gene to dog fibroblast cells, but they could not control where the virus inserted the gene.

Conventional, high - dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors» recurrence in more aggressive forms, researchers at Taipei Medical University and the National Institute of Cancer Research in Taiwan and University of California, San Francisco, have discovered.

The «target» cells on the other side of the BeWo barrier to the nanoparticles were human fibroblast cells, found in skin and connective tissue.

The research has also investigated the role of Rho - kinase inhibition on cellular - scale protein expression and stimulation of cellular differentiation of fibroblast cells.

Diluted and filtered liquid medium drawn from the fibroblast cell culture also killed breast and lung cancer cells.

Hamlyn, working with Richard Schmidt of the School of Pharmacy at the University of Wales in Cardiff, exposed human fibroblast cells to six fungi strains.

For many years, tattoos were thought to work by staining fibroblast cells in the dermal layer of the skin.

It spurred the fastest growth of fibroblast cells, with 17 per cent more cells formed after six days as in a control culture.

Imagine researchers» excitement, then, when Kyoto University's Shinya Yamanaka reported last year that his group had created embryolike cells directly, without transferring chromosomes, simply by injecting mouse fibroblast cells with four genes that are active in embryonic cells but not in adult ones.

- catenin pathway activates certain lncRNAs to directly control gene expression in skin fibroblast cells.»

Researchers used the CRISPR / Cas9 gene editing technique to introduce a segment of a human gene causing Huntington's, with a very long glutamine repeat region, into pig fibroblast cells.

Instead of dispensing ink, Organovo's bioprinter uses two robotic tips to deposit globs of cells — in this case, endothelial cells that line blood - vessel walls, smooth muscle cells that regulate vessel dilation and contraction, and structural fibroblast cells.

In a study published recently in the journal Carbon, the team grew human and mouse fibroblast cells (cells involved in wound healing) on flat graphene sheets and on wrinkled ones.

Following a cut to the skin, fibroblast cells rush to the wound and secrete a matrix that helps skin cells move into place, grow, and heal the injury.

These genes all help control actin, a protein used by fibroblast cells to move.

Special focus is placed on Rho - kinase inhibition, relating to its potential to promote and support extracellular matrix production in cultured chondrocytes and its role in fibroblast cells as a part of direct chemical cellular differentiation.

Cells were washed once with serum - free DMEM and then incubated in 10 % DMEM containing 10 μg / ml DiI - Ac - LDL for 4 h. Endothelioma cells and 3T3 fibroblast cells were used as a positive and negative reference, respectively.

Rho - kinase inhibitor Y - 27632 increases cellular proliferation and migration in human foreskin fibroblast cells

The potential of iPS cells to help treat everything from damaged heart tissue to Parkinson's disease, has prompted intensive research that has looked into the use of skin fibroblast cells as an alternative to controversial embryonic stem cells.

One of the many payoffs of the International HapMap Project was that it characterized genetic variation in fibroblast cell lines that could be ordered from Coriell for subsequent experiments.

They have already shown that they can transform human fibroblast cells into pluripotent stem cells, and now plan to start working on delivering the proteins needed to differentiate stem cells into specialized tissues.

SPARC regulates collagen interaction with cardiac fibroblast cell surfaces.

Mechanosensitivity of fibroblast cell shape and movement to anisotropic substratum topography gradients.

Multi-drug resistance protein 4 (MRP4)- mediated regulation of fibroblast cell migration reflects a dichotomous role of intracellular cyclic nucleotides.

Just this year, another group found that fibroblast cells (cells active in connective tissue) taken from mouse tails could be made into nerve cells, or neurons.

If fibroblasts could be used to create baby birds then the world of bird de-extinction would open up expansively, and the frozen fibroblast cell lines of endangered bird species at the San Diego Frozen Zoo could be used to rescue species on the verge of extinction.

A, DDX3 inhibited the colony formation ability of several tumor and normal murine fibroblast cells.

To explore the biological function of DDX3 on cell growth control, a colony formation assay was done in several tumor cell lines (HuH - 7, HCT116, and HeLa) and normal murine fibroblast cells (NIH 3T3) under the selection of G418.

The systematic characterization of somatic mutations fed nicely into a phylogenetic analysis, which revealed that all d42m1 derived clones were related (genetically speaking) to one another, while quite distinct from the other sarcoma (H31m1) as well as normal fibroblast cells.

Forced expression of DDX3 leads to the suppression of colony formation activity of HCC, cervical carcinoma, colon cancer, and murine fibroblast cells (see Fig. 1A).

Confocal images of sections of the seminiferous tubules illustrated the existence of various iPS cell - derived EGFP - positive cells, including flattened fibroblast cell - like myoid at the outermost layer of the tubules, spermatogonial stem cells with spherical nuclei closest to the basement membrane and spermatocytes with distinctive chromatin closer to the lumen than spermatogonial stem cells (Figure 6D).

For the first time, scientists have turned muscular dystrophy patients» fibroblast cells (common cells found in connective tissue) into stem...

Five beagles were created by cloning fibroblast cells that express a red florescent gene produced by sea anemones.

To further facilitate genome editing in pigs, we report here establishment of a pig line with Cre - inducible Cas9 expression that allows a variety of ex vivo genome editing in fibroblast cells including single - and multigene modifications, chromosome rearrangements, and efficient in vivo genetic modifications.

Mutations for mammoth hemoglobin, extra hair growth, fat production, down to nuanced climate adaptations such as slightly altered sodium ion channels in cell membranes have already been engineered into fibroblast cell lines.

Mouse fibroblast cells expressing HP1alpha, the human version of heterochromatin protein 1a.

The DP consists of a small group of fibroblast cells derived from the mesoderm.

Briefly, the retrovirus was transfected into DF1 chicken fibroblast cells using Superfect (Qiagen, Gaithersburg, MD) and viral particles were harvested over 1 week.

The generation of induced pluripotent stem cells from adult fibroblast cells to create iPS cells.

Proline is needed to build collagen, to increase collagen synthesis in human fibroblast cells.

Knowledgeable in starting, growing, and freezing skin fibroblast cell cultures while maintaining database of complete cell culture list.

Experienced and knowledgeable Laboratory Research Assistant providing cutting - edge research and development initiatives, working with fibroblast cell cultures and performing biochemical enzymatic analyses.

Not exact matches

Using patient's own tissue and specific combination of reprogramming factors, skin fibroblasts are successfully converted to cell type that... Continue reading Breakthrough Device Looks to Heal Organs

In a preliminary experiment, the team found that stem cells produced from fibroblasts of men with Klinefelter syndrome also lost the extra sex chromosome.

The team took small pieces of ear tissue from XXY and XYY mice, cultured them, and collected connective tissue cells known as fibroblasts.

They turned the fibroblasts into stem cells and noticed that in the process, some of the cells lost the extra sex chromosome.

These cells, called fibroblasts, help close wounds after skin has been cut.

Ueli Schibler of the University of Geneva showed in 1998 that the per genes of rat connective - tissue cells called fibroblasts are active according to a circadian cycle.