Sentences with phrase «a cell surface protein»

In another study, Rezende helped functionally characterize the specific fragments of the cell surface protein, Als5p, that allows the pathogenic fungus, Candida albicans, to bind to its host.

The protein is important because it is similar in structure to cell surface proteins in several pathogenic fungi.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

CRH, in turn, triggered production of the cell surface protein FasL; trophoblasts expressing FasL then form a protective shield of sorts around the embryo by forcing any attacking immune cells to self - destruct.

Unlike CD8 + DCs that express the cell surface protein CD205, CD8 — DCs, which are positive for the 33D1 antigen, are specialized for presentation on major histocompatibility complex (MHC) class II.

They identified these cells by looking for cell surface proteins called CD31 and CD146.

Some would simply crank their telomerase activity up even further; some would enhance the activity of drug - metabolizing enzymes that degrade the inhibitor; still others would change their cell surface proteins in ways that would make it harder for the drug to penetrate into the cell.

The data referred to cell surface proteins that supposedly defined the cells.

A cell can change the amount of these cell surface proteins by internalizing small portions of the membrane through endocytosis.

In 2006, researchers discovered the genetic defect behind FOP: A mutated version of the gene ACVR1, which in patients produces an overactive form of a cell surface protein called a transmembrane receptor.

STAR2 works by specifically binding to a cell surface protein called TNFR2, activating a signaling pathway that increases the number of T reg cells.

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family.

Researchers in the laboratory of Richard A. Axel, including Leonard Chess and Dan Littman, clone the genes for the CD4 [i] and CD8 [ii] T cell surface proteins.

Timothy Springer, with colleagues Michael L. Dustin and Charles A. Dinarello, identifies and characterizes adhesion molecules, a class of cell surface proteins that function in the interactions of immune cells with other cells, including antigen - specific recognition and cell trafficking: integrin LFA - 1 involved in cytoskeleton and signaling, and intracellular adhesion molecules (ICAMs), which are binding partners (ligands) for LFA - 1 and are increased in inflammatory and autoimmune disease.

Upregulated genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.

The system could be used for analyzing low expression cell surface proteins and for high - throughput screening for industrial enzyme production.

Targeting these proteins may be superior to targeting cell surface proteins because their elimination confers simultaneous insensitivity to multiple cell - surface inhibitory receptors.

Breast cancer stem cells wear a cell surface protein that is part nametag and part bull's eye, identifying them as...

«That is why detecting early esophageal cancer with fluorescent probes to highly expressed cell surface proteins are necessary.»

«For example, cell surface proteins that respond to growth factors can be deregulated in some cancers.»

These studies led to identification of a cell surface protein that is a useful marker of positive selection and is a likely regulator of mature lymphocyte and APC function.

These capacities are more prevalent in cancer cells that feature a specific cell surface protein called CD44, Tang said.

The experiments identified a previously uncharacterized gene as essential for intoxication by diphtheria toxin and exotoxin A toxicity, and a cell surface protein needed for cytolethal distending toxin toxicity.

Known as MHC (Major Histocompatibility Complex) genes, they code for cell surface proteins.

A library of recombinant P. falciparum secreted and cell surface proteins was expanded by 20 additional proteins, which were shown to express at usable levels and contain conformational epitopes.

People who had a better antibody response to the vaccine after 28 days had higher levels of HLA - DR (a cell surface protein which is a marker for immune stimulation) on a specialised type of dendritic cell.

Chemicals in these particular types of leafy green vegetables trigger a powerful immune boosting activity in cell surface proteins (AhR proteins) found on the surface of white blood cells, otherwise known as lymphocytes.

These immune cell surface proteins in themselves help the body by making our DNA less vulnerable to attack by our immune system which may have gone on the attack of foreign particles in our blood, such as dead cells, parasites, viruses, pollens and more.

The Major Histocompatibility Complex (MHC) is a region of the genome that contains genes that code for a group of cell surface proteins known as Dog leukocyte antigens (DLA).

The Major Histocompatibility Complex (MHC) is a region of the genome in dogs that contains genes that encode a group of cell surface proteins known as Dog leukocyte antigens (DLA).

Not exact matches

In 1987 a group of French scientists had discovered a protein protruding from the surface of T cells, which they called CTLA - 4.

Antigens are proteins on the surface of blood cells that can cause a... Continue Reading →

The expert answers: «Having Rh negative blood means that a protein, the D antigen, is not present on the surface of the red blood cells.

According to the American Pregnancy Association, the Rh factor is a specific type of protein on the surface of red blood cells.

Phages identify and grab bacteria using proteins on their leglike tail fibers, which form a strong bond with compounds on the bacterial cell surface.

When similar analysis was performed on the db mice, it was found that the disrupted db gene was responsible for encoding a protein that functions as a leptin receptor: When it binds circulating leptin at the cell surface, it sets in motion a biochemical cascade inside the cell.

To target liposomes to certain tissues or cells, such as tumour cells, a specific binder of a unique protein (an antigen) on the targeted cell, known as a monoclonal antibody, must be linked to the liposome surface.

The antibody binds to a protein on the surface of T cells called the PD - 1 receptor.

The «acid spit» chewed up surface proteins that the pathogen uses to attach to and invade human cells.

The protein expressed by the gene is thought to bind to serotonin receptor molecules and ferry them to the cell surface, positioning them to receive serotonin's signals from neighboring cells.

The effort is complicated because there are some 16 types of key surface proteins (hemagglutinin) that help the virus bind to host cells, in addition to the several varieties of viral neuraminidase proteins.

Before Krieger started tinkering with the mouse gene SCARB1, he had identified SRB1, a protein found on the surface of the liver cells, as that dock for HDL.

«We discovered that Neu1, a protein nicknamed after «neuraminidase 1,» turns the absorption of sugar «on» or «off» in body cells, by regulating the amount of sialic acid on the surface of cells,» Dr. Pshezhetsky explains.

Further study revealed that these so - called immune proteins are actually present on the surface of certain nerve cells, but that they functioned differently in the brain than they did in the rest of the body; rather than scouting for germs, they influenced signals sent between neurons.

After 24 days the cells had developed surface proteins that identified them as specific types of lung cell, including alveolar cells, which allow the exchange of gases, and cilia, which expel bacteria and dirt (Respiratory Research, DOI: 10.1186 / 1465-9921-10-105).

When they looked closely, however, they noted that the transformed cells had surface proteins that were common to stem cells.

This group of proteins is on the surface of almost every cell in your body.

In their study, which has just been published in the journal PNAS, the researchers demonstrate that the defence protein docks on to a specific target in the nematode: a modified sugar found on the surfaces of the worm's intestinal cells but also on those of molluscs like snails.

But the London researchers have shown a few small changes in the shape of a surface protein were all it took to enable the bird version of Spanish flu to bind onto human cells.

The team found that after exposure to chemotherapy, the cells began developing physical markings usually seen in CSCs, including receptors on the cell surface to which specific proteins can bind.