Sentences with phrase «a549 lung adenocarcinoma»

Reduced expression of the protein ANNEXIN - A1 correlated with higher stemness indices in samples of lung adenocarcinoma.

A large - scale genetic study of the links between telomere length and risk for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma.

They found that longer telomeres were significantly associated with increased risk for lung cancer — specifically lung adenocarcinoma, which more than doubled in risk for every 1000 base pair increase in telomere length.

They found that 64 percent of lung adenocarcinoma patients had at least one oncogenic driver gene.

«The positive association between telomere length and lung adenocarcinoma should be further investigated with the long term goal of improving prediction and prevention of this common cancer subtype.»

In patient samples of lung adenocarcinoma, 3 percent were found to have HER2 amplification and another 3 percent were found to have HER2 mutation.

The squamous lung cancer and lung adenocarcinoma type are the two most common types of lung tumor.

Likewise, an analysis tissue samples from patients with lung adenocarcinoma with no or low C / EBPα expression revealed that those with lower levels of BMI1 were more likely to survive, a pattern that has prognostic value, the researchers wrote.

Even some known cancer genes for lung adenocarcinoma, one of the most intensively studied cancers, haven't popped out in cancer genome surveys.

The virus, however, grew efficiently in a human A549 lung adenocarcinoma cell line.

We next attempted to culture TMAdV in an A549 (human lung adenocarcinoma) cell line, a BSC - 1 (African green monkey kidney epithelial) cell line, and PMK (primary rhesus monkey kidney) cells (Fig. 5).

In this study, the researchers focused on a type of non-small cell lung cancer called lung adenocarcinoma, which accounts for about 40 percent of lung cancers.

The flow chart displays 10 passages (P1 — P10) of TMAdV cultured in human lung adenocarcinoma (A549, orange), primary rhesus macaque kidney (PMK, brown), or established African green monkey kidney (BSC - 1, green) cells.

A549 (human lung adenocarcinoma) and BSC - 1 (African green monkey kidney epithelial) cell lines as well as PMK (primary rhesus monkey kidney) cells are routinely maintained at the Viral and Rickettsial Disease Laboratory (VRDL) branch of the California Department of Public Health.

Research Paper Hepatotoxicity in Advanced Lung Adenocarcinoma: A Retrospective Study of 2108 Cases Jie Qian, Xueyan Zhang, Bo Zhang, Ping Gu, Lin Wang, Baohui Han J. Cancer 2018; 9 (9): 1607 - 1613.

One major change is the recommendation to test for alterations to the gene ROS1 in all cases of lung adenocarcinoma, which make up about half of all cases of non-small cell lung cancer.

Verma has successfully developed lentiviral vector - mediated mouse models for glioblastoma, lung adenocarcinoma and small cell lung cancer (SCLC).

Drs. Ana Robles, Delphine Lissa, Curtis Harris, and collaborators at the National Cancer Institute in Bethesda, Maryland, sought prognostic biomarkers that could predict relapse in patients with stage I lung adenocarcinoma, a major subtype of NSCLC.

Gamma secretase inhibition by BMS - 906024 enhances efficacy of paclitaxel in lung adenocarcinoma.

Xia Y, Liu Y - L, Xie Y, Zhu W, Guerra F, Shen S, Yeddula N, Fischer W, Low W, Zhou X, Zhang Y, Oldfield E, Verma IM (2014) A combination therapy for KRAS - driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.

Researchers from the Broad Institute and elsewhere have identified novel mutations in a well - known cancer - causing pathway in lung adenocarcinoma, the most common subtype of lung cancer.

Validation of a cell cycle progression score for five - year mortality risk in patients with stage I lung adenocarcinoma.

«In recent years, we have made enormous progress in lung adenocarcinoma treatment by targeting EGFR, ALK, and other mutated proteins.

«It is quite striking that we have now identified an actionable mutation in over 75 percent of patients with lung adenocarcinoma, a significant improvement from a decade ago,» said Meyerson.

«Lung adenocarcinoma is the leading cause of human cancer death.

Lung adenocarcinoma, the most common form in the United States, develops in tissues near the outer parts of the lungs and can spread widely.

In this new study, published online July 9, 2014, in the journal Nature, researchers from the Cancer Genome Atlas (TCGA) Research Network, under the direction of Broad senior associate member Matthew Meyerson, examined the genomes, RNA, and some protein from 230 lung adenocarcinoma samples.

We will identify where the guideline strengthens or reaffirms the 2013 recommendations for patients with lung adenocarcinoma, as well recommendations for testing for several new genes.

2) Becker - Santos DD, Thu KL, Pikor LA, English JC, Vucic EA, MacAulay CE, Robinson WP, Jurisica I, Lockwood WW, Lam S, Lam WL (2016) The developmental transcription factor NFIB is a potential target of oncofetal miRNAs and has significant clinical implications in lung adenocarcinoma.

17) Thu KL, Vucic EA, Chari R, Zhang W, Lockwood WW, English JC, Fu R, Wang P, Feng Z, MacAulay CE, Gazdar AF, Lam S, Lam WL (2012) Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability.

, Lam S, Lam WL (2016) The developmental transcription factor NFIB is a potential target of oncofetal miRNAs and has significant clinical implications in lung adenocarcinoma.

3) Unni A *, †, Lockwood WW *, †, Zejnullahu K, Lee - Lin S, Varmus H (2015) Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma.

«Our combined findings demonstrate that p53 status represents a critical determinant in selection of therapeutic strategies for lung adenocarcinoma patients.»

, Lee - Lin S, Varmus H (2015) Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma.

«Our data show that control of survival of lung adenocarcinoma cells by Notch1 requires a functional p53,» they wrote.

21) Somwar R, Erdjument - Broonage H, Larsson E, Shum D, Lockwood WW, Yang G, Sander C, Ouerfelli O, Tempst PJ, Djaballah H, Varmus H (2011) SOD1 is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

As our aim was to indicate general tissue specific carcinogenic properties, we used all the known subtypes of these cancers, including (1) hyper mutated and non-hypermutated colon cancers; (2) lung adenocarcinomas, large cell carcinomas, and squamous cell carcinomas (3) HER2 positive, basal, luminal A and luminal B breast cancers; and (4) hepatitis B or hepatitis C, cirrhosis or other agent causing hepatocellular carcinoma data.

DIM's history for cancer prevention and therapy began when a mouse study showed its promising results in tobacco smoke, carcinogen - induced, lung adenocarcinoma.

Not exact matches

Adenocarcinoma is the most common type of lung cancer in the United States with approximately 130,000 people diagnosed each year.

The authors report that higher levels of physical activity compared to lower levels were associated with lower risks of 13 of 26 cancers: esophageal adenocarcinoma (42 percent lower risk); liver (27 percent lower risk); lung (26 percent lower risk); kidney (23 percent lower risk); gastric cardia (22 percent lower risk); endometrial (21 percent lower risk); myeloid leukemia (20 percent lower risk); myeloma (17 percent lower risk); colon (16 percent lower risk); head and neck (15 percent lower risk), rectal (13 percent lower risk); bladder (13 percent lower risk); and breast (10 percent lower risk).

His study looked at adenocarcinoma, a type of lung cancer in the air sacks that afflicts both smokers and non-smokers.

After lung cancer, adenocarcinoma of the prostate is the biggest cancer killer of men in the Western -LSB-...]

She says they can now identify the mechanisms that cause tumor growth in half of all adenocarcinomas, a family of cancer that affects skin and other tissue, including the lungs.

Adenocarcinomas account for some 40 percent of all lung cancers diagnosed.

Adenocarcinoma of the Appendix, Anal cancer, Breast Cancer, Cancer, Squamous cell carcinoma, Colorectal Cancer, Esophageal Cancer, Esthesioneuroblastoma, Hodgkin lymphoma, Intrahepatic cholangiocarcinoma, Laryngeal cancer, Lip and oral cavity cancer, Liposarcoma, Liver cancer, Multiple myeloma, Nasopharyngeal carcinoma, Non-small cell lung cancer, Oral cancer, Osteosarcoma, Pancreatic cancer, Rectal Cancer, Salivary Gland Cancer, Stomach cancer, Synovial sarcoma, Testicular cancer, Tongue cancer, Vaginal cancer, Bladder cancer, Cervical cancer, Prostate cancer, Non-Hodgkin lymphoma, Brain Cancer, Thyroid Cancer, Ewing Sarcoma, Extrahepatic bile duct cancer, Melanoma

To date, the TCGA Research Network has generated data and published analyses on glioblastoma multiforme, ovarian serous adenocarcinoma, colorectal adenocarcinoma, lung squamous cell carcinoma and invasive breast cancer.

In certain tumor groups, subtypes have been included, e.g. breast cancer includes both ductal and lobular cancer, lung cancer includes both squamous cell carcinoma and adenocarcinoma and liver cancer includes both hepatocellular and cholangiocellular carcinoma etc..

Although smoking is the main risk factor, adenocarcinoma is also the most common type of lung cancer among lifelong non-smokers, and the risk of lung cancer is increased by 20 to 30 percent by exposure to secondhand smoke.

Nearly 80 % of all lung tumors are adenocarcinomas.

Since adenocarcinomas of the kidney frequently metastasize to the lung, coughing and labored breathing might also be seen.