Sentences with phrase «abl gene fusion»
Not exact matches
The activity of tyrosine kinases is typically regulated in an auto - inhibitory fashion, but the BCR - Abl fusion gene codes for a protein that is «always on» or continuously activated leading to unregulated cell division (i.e. cancer).
https://en.wikipedia.org/
This gene encodes for a Bcr - abl fusion protein.
Previous reports have shown that in a genetic abnormality called Philadelphia chromosome, fusion of ABL and BCR genes cause leukemia.