Sentences with phrase «achm2 affected offspring»

Like the sugary treats fastened to the witch's cottage, the saccharine assurances from the ER staff that this doctor was keen to help OI patients had obscured his intentions: They had brought us to a eugenicist who wished to push any of my future OI - affected offspring into the oven.

The loss of human and social capital to our state had Jessie aborted her three OI - affected offspring would have been substantial.

Let us imagine Jessie fell under the spell of the coercive eugenicist my wife resisted and agreed to abort her three OI - affected offspring — Lloyd, Mabel, and Cyril — while retaining her firstborn Laura as her sole «genetically pure» child.

As more and more traits are attributed to epigenesis and inheritance, from diabetes to cancer risk to personality to homosexuality, mothers are increasingly being scrutinized for the way even their smallest decisions affect their offspring.

«Mothers» sleep, late in pregnancy, affects offspring's weight gain as adults.»

The process by which a mother's diet during pregnancy can permanently affect her offspring's attributes, such as weight, could be strongly influenced by genetic variation in an unexpected part of the genome, according to research led by Queen Mary University of London (QMUL).

two unaffected parents and an affected offspring?

There was no strong evidence that the interventions affected offspring outcomes such as stillbirth, underweight or overweight births, or admission to a neonatal intensive care unit.

«Both studies pointed to one direction: mothers» body weight affected their offspring's weight.»

I was fascinated to learn that trauma experienced by mice can affect their offspring through epigenetic transfer (6 November, p...

Disturbances of the placenta's bacterial community may explain why some women give birth prematurely, and could also be one of the ways that a woman's diet affects her offspring's gut bacteria, and as a result the child's disease risk.

After analyzing news coverage levels, the researchers administered a survey in March 2013 to 822 new and expectant mothers to determine if they incidentally encountered, or «scanned,» news about chemicals in the prior 6 months and how such scanning was related to their behavior to reduce chemical exposures that might affect their offspring.

To think that we could smoke and have terrible choices and have that not affect our offspring is just so wrong and so naïve and so unfortunate.

Animal studies involving rats do suggest that flax affects the offspring of pregnant rats.

How do the expectations or life legacy of fathers affect their offspring in this story?

Owners or adopters of non-purebred dogs can also help by sterilizing their pets before they become sexually mature to prevent any possibility of producing affected offspring.

Stud Dog owners should disclose to owners of bitches who wish to use their dog that the dog is a known carrier (by virtue of it being out of an affected parent or having itself sired affected offspring, or by virtue of it having been genetically identified as a carrier for the Cord1 mutation), even though the Stud Dog may himself have a current clinically clear eye certificate.

If screening detects that a dog is predisposed to a genetic disease (or likely to produce affected offspring) and / or perhaps already in the early stages of the disease, then no breeding can take place under the scheme.

Through DNA testing we can control this genetic disorder now and avoid producing affected offspring.

It is not a matter of simply avoiding Cyd and Jordan in a pedigree, as there are many unidentified carriers in the breed, and at present it is not possible to identify a carrier, unless it has produced an affected offspring.

Test breeding a suspected carrier to an affected animal will confirm carrier status if affected offspring are produced, but this is not a very practical solution.

In order to avoid producing crd2 - affected offspring, at least one dog of any breeding pair should be homozygous Normal / Clear (See chart below).

In the Cocker spaniel we have found that the risk of getting affected offspring increases when one or more parents are affected by distichiasis, suggesting the accumulation of presumed predisposing genes.

In order to avoid producing affected offspring, carriers of the rcd1b mutation should never be bred to other carriers or to affected dogs (see chart below).

The relative risk (RR) of producing affected offspring was found to increase with the number of affected parents in the breeding combination.

However, dogs with mild disease can produce severely affected offspring.

It is important to remember that breeding · clear · dogs does not absolutely guarantee that puppies will be unaffected, as it is not usually possible to determine which genes both dam and sire carry and how their combinations will affect offspring.

When clinically normal dogs produce affected offspring, it strongly suggests the disease is inherited as a simple recessive (or potentially a polygenic — multiple gene) trait, and both parents carry one «bad» copy of the gene causing the disease.

Five litters (23 dogs) without affected dogs were born to matings between parents that had both been known to produce affected offspring.

Havanese which repeatedly produce affected offspring should be removed from the breeding program, and their offspring should not be used for breeding.

By using relative - risk assessment to breed him to a female that is at low risk of being a carrier, you can prevent affected offspring, and select a quality son for replacement.

In the miniature schnauzer, a swallowing condition is inherited but appears to be complex with some, but fewer, affected offspring from outcross breedings (Cox et al., 1980).

Animals that produced affected offspring were presumed carriers.

Healthy dogs which produce multiple affected offspring, particularly with different mates, should be withdrawn from breeding.

Neither the parents nor the affected offspring need to have the DNA test unless there are doubts about the accuracy of the diagnosis.

Most the affected offspring in these litters had choroidal hypoplasia.

The results revealed the dog's genotype and enabled breeders to avoid producing affected offspring by not doing crosses which could produce them.

If they should produce cataract - affected offspring, they should be pulled from breeding.

Valuable dogs carrying unwanted genes which formerly might have been removed from breeding programs could be bred because breeders could determine the genotypes of prospective mates and eliminate the possibility of producing affected offspring.

If a dog is determined to be a carrier of CEA, either through testing or because it has affected offspring, it should be bred but only to a mates that have been tested clear of the mutation.

There is little chance of eliminating all carriers from a breeding program since they are not apparent «until affected offspring are produced.

Conversely, if the disease gene is rare in a breed, it is improbable that affected offspring will result, though it would be more likely when line - breeding than outcrossing.

In other words, at least one of any breeding pair should be homozygous Normal / Clear of crd3 to ensure that no crd3 - affected offspring are produced.

In order to avoid producing crd3 - affected offspring, carriers of the mutation should never be bred to other cd3 - carriers.

Fortunately the majority of their mates were Normal for prcd and so relatively few Affected offspring have been produced.

With an array of problems that may have a common end result of blindness, informed breeders will not breed affected animals because those with «mild disease» may still produce severely affected offspring.

The University of Minnesota Canine Genetics Laboratory website also contains a portable document format (pdf) form detailing IM: Inflammatory Myopathy (Myositis) Test Result Interpretation which reveals, amongst other details, that both parents must be carriers to produce affected offspring.

A dog that is homozygous affected (meaning he has two copies of the mutation) will always produce affected offspring.

In order to avoid producing affected offspring, at least one parent of any litter should be DNA tested and shown to be Normal / Clear of the mutation.

AFFECTED parent bred to a NORMAL parent will not produce any AFFECTED offspring, but all will be CARRIERS.