ERK1 / 2 activity was inhibited using U0126, PI3K -
AKT kinase activity was inhibited using LY294002 and JNK activity was inhibited using SP600125 (all were from Calbiochem, USA).
Not exact matches
AKT is a downstream effector of phosphatidylinositol 3 -
kinase (PI3K) and a critical mediator of mammalian target of rapamycin (mTOR)
activity (6).
In addition, caffeine may increase the
activity of several signaling enzymes, including the calcium - dependent protein
kinase and protein
kinase B (also called
Akt), which have roles in muscle glucose uptake during and after exercise.