Not exact matches
Previous studies of genetic
alterations in lymphoma and lung cancer have found that certain genetic mutations — specifically when part of a gene breaks off and gets fused to another — can inappropriately switch on
ALK, driving cancer cells to grow and divide.
Among patients with non-small cell lung cancer (NSCLC) fueled by
ALK gene
alterations who were being treated with crizotinib (Xalkori), a decrease in the number of circulating tumor cells (CTCs) harboring increased copies of the
ALK gene over the first two months of treatment was associated with increased progression - free survival.
Abnormalities that are commonly seen in Cushing's patients are: Elevated liver enzymes (
Alk Phos, + / - ALT), + / - increased blood glucose, unconcentrated urine (specific gravity less that 1.025), protein in urine,
Alterations in blood cell counts (increased neutrophils, decreased lymphocytes and eosinophils), and + / - nucleated red blood cells.