Sentences with phrase «aneuploidy nested»

ART - 0006: MELISSA STUDY: MATERNAL BLOOD IS SOURCE TO ACCURAT ELY DIAGNOSE FETAL ANEUPLOIDY NESTED CASE: CONTROL ANALYSES T (Private)

Not exact matches

Half or more (sometimes all) embryos in a particular IVF treatment cycle are aneuploid, and while we can't prove this, we suspect that the majority of natural conceptions are affected by aneuploidy as well.

Several researchers interviewed, after asking to go off the record, erupted in venomous attacks on Duesberg, saying that aneuploidy is the result of cancer, not the cause.

But recently a number of mainstream scientists have come around, agreeing that aneuploidy may play a role (even if not an exclusive one) in cancer.

Although aneuploidy does not bring in new genetic sequences, it does make possible another kind of genetic diversity — in which the extra genes produce extra proteins, resulting in an organism that differs from its parents.

Berman agrees that the possibility that aneuploidy can confer benefits «isn't what the textbooks say is supposed to happen.

«Unfortunately our paper suggests that tumors don't even need to be heterogeneous genetically, the very fact that they have aneuploidy could lead to very variable outcomes, and that represents a significant challenge for cancer therapy,» Amon says.

Aneuploidy originates during cell division, when the chromosomes do not separate properly or are not equally partitioned between the two daughter cells.

The cells» response to environmental changes also varied considerably, suggesting that aneuploidy has an impact on the robustness of many, if not all, biological processes.

If having one extra chromosome caused an anti-tumorigenic effect in pre-malignant cells, then perhaps aneuploidy was not, in itself, a direct cause of cancer.

«Aneuploidy is driving cancer, not simply a consequence of it,» said Elledge.

In contrast to the view that aneuploidy is deleterious, the aneuploid unisexually generated isolates MN35 (n +113) and MN55 (n +19) were as virulent as the euploid wild - type parent, despite their modest TS growth at 37 °C on YPD rich media in vitro (Figure 7).

For reasons not completely understood, we have an extraordinarily high rate of aneuploidy, with ~ 10 % of clinically recognized pregnancies having a fetus with too many or too few chromosomes.

However, the etiology of aneuploidy remains a complex puzzle that we do not fully understand.

Aneuploidy scans are not routinely performed, as many normal pregnancies may have some of these features - ie there is a high false - positive rate.