D - F, Hippocampal BDNF was increased by exercise (D;
ANOVA effect of exercise, p = 0.041).
E — G, In contrast, exercise increased hippocampal BDNF levels across all three genotypes (E,
ANOVA effect of exercise, p = 0.035), with no change in α - tubulin as a loading control (F).
Not exact matches
Analysis
of CD68 immunostaining in the frontal cortex revealed an
effect of genotype (
ANOVA, p < 0.0001) and a strong trend for an
exercise effect (
ANOVA exercise effect, p = 0.051).
Significant main
effects or interactions in two - way
ANOVA were followed by Sidak's post hoc test to compare sedentary versus
exercise mice
of each genotype.