I am very interested in getting feedback from pet parents that have had the opportunity to use
Apoquel in their dogs.
IMPORTANT SAFETY INFORMATION: Do not use
APOQUEL in dogs less than 12 months of age or those with serious infections.
Not exact matches
Apoquel is a JAK - 1 inhibitor that is especially formulated and duly approved by the FDA for use
in the control and management of intense itching
in dogs.
As an allergy medication for dogs,
Apoquel provides instant relief from itching and may help prevent the development of secondary bacterial infections brought about by the loss of skin integrity inherent
in incessant scratching.
«A Blinded Randomized Placebo - controlled Trial of the Efficacy and Safety of the Janus Kinase Inhibitor Oclacitinib (
Apoquel ®) in Client - owned Dogs with Atopic Dermatitis» was designed in support of a new drug registration to evaluate the safety and efficacy of A
Apoquel ®)
in Client - owned Dogs with Atopic Dermatitis» was designed
in support of a new drug registration to evaluate the safety and efficacy of
APOQUELAPOQUEL.
Home / NEWS & MEDIA / pivotal data demonstrating efficacy and safety of
apoquel ® published
in veterinary dermatology
Missing a dose will lead to some changes
in the plasma levels of the active ingredient of
Apoquel.
APOQUEL is a targeted new approach to rapidly and safely stop the cycle of itch and inflammation associated with allergic skin disease
in dogs.
APOQUEL is the only animal health product approved for both the control of pruritus associated with allergic dermatitis and the control of atopic dermatitis
in dogs over 12 months of age.
APOQUEL ® should not be used
in dogs less than 12 months of age or
in dogs with serious infections.
Eighteen board - certified veterinary dermatologists
in the United States enrolled a total of 299 dogs 1 year of age or older to receive
APOQUEL or excipient - matched placebo at a dose of 0.4 - 0.6 mg / kg twice - daily for 14 days, and then once - daily at the same dose for up to 112 days.
Recent advancements have been made
in the area of antipruritic medications for animals and there are now effective medications with fewer long term side effects such as cyclosporine (Atopica) and oclacitinib (
Apoquel).
A blinded, randomized, placebo - controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (
Apoquel ®)
in client - owned dogs with atopic dermatitis.
Yes,
APOQUEL is safe to be used with other treatments such as vaccines, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and other allergy medications.4 The use of
APOQUEL has not been evaluated
in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.
Weekly, bi-monthly or monthly medicated baths, using daily ear washes, Hypoallergenic prescription diet food and treats, medications (
Apoquel, Atopica, antibiotics, antifungals, allergy immunotherapy, etc), routine lab work and exams are necessary to keep your pet
in their best health to avoid flare ups and addressing any skin issues before they become worse.
APOQUEL is prescribed by your veterinarian to control itch and stop inflammation associated with allergic or atopic dermatitis
in dogs 12 months and older.
Gonzales AJ, Bowman JW, Fici GJ, Zhang M, Mann DW, Mitton - Fry M. Oclacitinib (
APOQUEL ®) is a novel Janus kinase inhibitor with activity against cytokines involved
in allergy.
These occurred
in only a small percentage of dogs treated with
APOQUEL.
The most common side effects seen
in dogs administered
APOQUEL were vomiting and diarrhea.
APOQUEL was approved by the U.S. Food and Drug Administration
in May 2013 and is the first and only Janus kinase (JAK) inhibitor approved for veterinary use.
APOQUEL should not be used
in breeding dogs, or pregnant or lactating dogs.
«
APOQUEL is just one example that shows how we are continuing to invest
in innovative new approaches that help veterinarians address real - world conditions, such as allergic and atopic dermatitis.»
«Pet owners who complained that their dogs would wake them up
in the middle of the night due to intense itch have told me that after treatment with
APOQUEL, the household can sleep more peacefully,» Dr. Lewis said.
We are sorry to announce that due to a pharmaceutical backorder, The Drake Center is experiencing a shortage of
Apoquel, a new medication recently released on the veterinary market to relieve itching
in dogs with allergic skin disease.
A masked, multisite, well - controlled study of 436 dogs conducted at 26 veterinary clinics
in the US evaluated the effectiveness and safety of
APOQUEL, dosed orally twice daily (BID) at 0.4 to 0.6 mg / kg for the control of pruritus associated with allergic dermatitis, including flea allergy, food allergy, contact allergy and atopic dermatitis
Apoquel works regardless of the type of allergy and can start to relive the itch
in as little as four hours.
In a trial of dogs with atopic dermatitis, dogs treated with APOQUEL experienced a significant and long - term reduction in itch and inflammation at day 28 of the stud
In a trial of dogs with atopic dermatitis, dogs treated with
APOQUEL experienced a significant and long - term reduction
in itch and inflammation at day 28 of the stud
in itch and inflammation at day 28 of the study.
The first drug
in its class to be approved for veterinary use,
Apoquel is specifically designed to address the source of the itch, providing fast - acting relief and minimal side effects.
With
APOQUEL, veterinarians now have a first -
in - class treatment choice that targets the itch of allergic skin conditions at its source.
In a trial of dogs with allergic dermatitis,
APOQUEL produced rapid onset of efficacy within 24 hours.
In cases where
APOQUEL treatment was continued, success rates remained constant through day 112.
APOQUEL has not been evaluated
in combination with systemic immunosuppressive agents such as glucocorticoids or cyclosporine.
In addition,
Apoquel can be used for both acute and chronic conditions, which is especially wonderful for those dogs needing long - term itch control with minimal side effects.
Florham Park, N.J. — August 13, 2013 — Results of a new pivotal study show that
APOQUEL ® (oclacitinib tablet) provides effective and safe control of pruritus associated with allergic dermatitis
in dogs with a rapid onset of efficacy within 24 hours and without the commonly reported side effects of steroids.
The most common side effects observed
in dogs treated with
APOQUEL were vomiting (2.3 %
in APOQUEL - treated dogs compared to 1.8 %
in placebo treated dogs) and diarrhea (2.3 %
in APOQUEL - treated dogs compared to 0.9 %
in placebo treated dogs).
APOQUEL produced rapid onset of efficacy within 24 hours - within the first day of treatment, pruritus scores were reduced by at least 2 cm on a 10 cm VAS scale
in 44 % of the
APOQUEL - treated dogs compared with 19 % of the placebo - treated dogs.
About the Study The study, «Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions
in dogs with canine allergic dermatitis,» was conducted as a double - masked, placebo - controlled clinical trial aimed to evaluate the safety and efficacy of
APOQUEL compared with placebo.
APOQUEL is the only animal health product approved for the control of pruritus associated with allergic dermatitis and the control of atopic dermatitis
in dogs over 12 months of age.
In previously reported laboratory studies, APOQUEL inhibited IL -31-induced pruritus in dogs faster than oral prednisolone and dexamethason
In previously reported laboratory studies,
APOQUEL inhibited IL -31-induced pruritus
in dogs faster than oral prednisolone and dexamethason
in dogs faster than oral prednisolone and dexamethasone.
Holistic veterinarian Deva Khalsa VMD describes how these drugs work
in her articles on Atopica and
Apoquel.
In both studies, dogs that remained on
APOQUEL beyond one week experienced continuous improvement throughout the course of the study.
In a trial of dogs with allergic dermatitis, treatment success, as defined by owner - assessed decrease in pruritus, occurred in 67 percent of dogs treated with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatmen
In a trial of dogs with allergic dermatitis, treatment success, as defined by owner - assessed decrease
in pruritus, occurred in 67 percent of dogs treated with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatmen
in pruritus, occurred
in 67 percent of dogs treated with APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatmen
in 67 percent of dogs treated with
APOQUEL vs. 29 percent of dogs treated with placebo after one week of treatment.
In a clinical trial of dogs with atopic dermatitis, treatment success for pruritus occurred in a significantly greater percentage of the dogs treated with APOQUEL (66 percent) vs. (4 percent) of dogs treated with placebo (p < 0.0001
In a clinical trial of dogs with atopic dermatitis, treatment success for pruritus occurred
in a significantly greater percentage of the dogs treated with APOQUEL (66 percent) vs. (4 percent) of dogs treated with placebo (p < 0.0001
in a significantly greater percentage of the dogs treated with
APOQUEL (66 percent) vs. (4 percent) of dogs treated with placebo (p < 0.0001).
The frequency and type of adverse events were similar between
APOQUEL - and placebo - treated dogs
in short - term trials.
«The good news is that Zoetis» revolutionary treatment for allergic itch,
Apoquel, can help your dog
in as little as four hours.
Apoquel is used to treat and control itching and inflammation
in dogs resulting from a variety of causes, including flea allergy, food allergy, contact allergy and atopic dermatitis.
The use of
Apoquel has not been evaluated
in combination with glucocorticoids, cyclosporine, or other systemic immunosuppressive agents.
Apoquel is not for use
in breeding dogs, or pregnant or lactating bitches.
«Efficacy and safety of oclacitinib (
APOQUEL) compared to cyclosporine (Atopica, Novartis Animal Health) for the control of atopic dermatitis
in client - owned dogs»
«Efficacy and safety of oclacitinib (
APOQUEL) compared to prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis
in client - owned dogs»