Sentences with phrase «atpase subunit»

His experience across subunits of the conventional marketing team allows him to execute it.

The DNA molecule is an extremely long chain of strictly ordered subunits, a length of several hundred to several thousand of which is called a gene.

But the point is that Faith and Order, which historically was the premier enterprise of the council, ended up as a subunit of a unit.

Something major has happened when the budget of CCPD, a subunit within one unit, is three times larger than the combined budgets for the three historic functions that are now subsumed in the first unit.

Indian theologian Stanley Samartha, the first director of the subunit on dialogue, while agreeing about the need for mission and conversion, called for a much more positive theological appreciation of the role of world religions in God's mission.

Three fairly well - defined subunits appear, which at one time were probably three separate cycles of stories.

The subunits center in (1) Abraham and Isaac, 12 - 26; (2) Jacob (and Esau), 27 - 36; (3) Joseph, 37 - 50 (excepting 38 which deals with Judah and Tamar).

It has been estimated that 5 % to 10 % of infants who die from SIDS have novel mutations in the cardiac sodium or potassium channel genes that result in long QT syndrome as well as in other genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.

Ban and Poul Nissen, a membrane protein researcher at the Aarhus University in Denmark who was also doing a postdoc in Steitz's lab at the time, pushed to determine the structure of the large subunit of the ribosome at high resolution.

«All subsequent structures of the whole ribosome or other [large] subunits have depended on this structure» that Ban produced, «and it was a tour de force,» writes Ramakrishnan, who has never collaborated with Ban.

Ban chose to work on one of the most difficult problems in structural biology: imaging the active site of the ribosome, a site within the large subunit of the ribosome where the bonding of individual amino acids into a protein chain is catalyzed.

TERT is a subunit of the enzyme telomerase, which is a widely known enzyme because it has been touted as an anti-aging enzyme.

«The applications for this thing are kind of endless,» says chemist Christopher Cahill of George Washington University in Washington, D.C. Choosing the right linker molecule between subunits could lead to even roomier crystals or give them other useful chemical properties, he says.

They linked the subunits with clusters of zinc acetate to create a scaffold riddled with wide channels, then soaked the crystals in various large organic molecules to test their sponginess and ability to sort by size.

The research, published and featured in the Spot Light section of the December edition of the Journal of Virology, examines a previously unknown connection between flaviviruses — a classification of viruses that include West Nile virus, Dengue virus and tick - borne encephalitis virus — and organelles (a specialized subunit within a cell) known as peroxisomes that help coordinate the body's immune responses.

RHPs are composed of four types of monomer subunits, each with chemical properties designed to interact with chemical patches on the surface of proteins of interest.

They identified two proteins, neuroplastin and basigin, as previously unrecognized auxiliary subunits of PMCAs.

Crystal structures of the 30S ribosomal subunit in complex with messenger RNA and cognate transfer RNA in the A site, both in the presence and absence of the antibiotic paromomycin, have been solved at between 3.1 and 3.3 angstroms resolution.

In the presence of Gs alpha, the alpha subunit of the G protein that activates adenylyl cyclase, one form of adenylyl cyclase was inhibited by beta gamma, some forms were activated by beta gamma, and some forms were not affected by beta gamma.

Structures of a 10 - subunit yeast RNA polymerase II have been derived from two crystal forms at 2.8 and 3.1 angstrom resolution.

It spans both ribosomal subunits with its amino - terminal domain positioned adjacent to the aminoacyl acceptor stem and its carboxyl - terminal domain positioned next to the anticodon stem - loop of the P site — bound initiator tRNA.

The alpha 7 beta 7 beta 7 alpha 7 subunit assembly has 72 - point group symmetry.

Metalloreceptors simultaneously bind organic molecules and metal ions; speleands combine polar and nonpolar binding subunits.

Cyclic adenosine monophosphate (cAMP)- dependent protein kinase, labeled with fluorescein and rhodamine on the catalytic and regulatory subunits, respectively, was injected into Aplysia sensory neurons either in culture or in intact cell clusters.

G protein beta gamma subunits have been found to have regulatory effects on certain types of adenylyl cyclase.

These results led to three conclusions about the chemical nature of ion binding sites in the conduction pathway: The channel contains two identical titratable sites, even though there are more than two (probably four) identical subunits; the sites are formed by glutamate residues that have a pKa (where K (a) is the acid constant) of 7.6; and protonation of one site does not perturb the pKa of the other.

The appearance of the variant after starch - gel electrophoresis of the hemolysates supports the concept that the lactic dehydrogenase isozymes are determined by the interaction of two subunits which are under separate genetic control.

Analysis of crosslinked complexes of M1 RNA, the catalytic RNA subunit of ribonuclease P from Escherichia coli, and transfer RNA precursor substrates has led to the identification of regions in the enzyme and in the substrate that are in close physical proximity to each other.

Plasticity of mature hippocampal CA1 synapses is dependent onl - α - amino -3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors containing the glutamate receptor A (GluR - A) subunit.

The study revealed that CSN6, a subunit of a protein complex known as COP9 signalsome, is overexpressed in colorectal cancer tissue samples.

Cognate transfer RNA (tRNA) binding induces global domain movements of the 30S subunit and changes in the conformation of the universally conserved and essential bases A1492, A1493, and G530 of 16S RNA.

The 673 - kilodalton protease complex consists of 14 copies of two different subunits, alpha and beta, forming a barrel - shaped structure of four stacked rings.

Energy transfer between the subunits, a measure of cytosolic cAMP concentration -LRB-[cAMP]-RRB-, and compartmentation of the dissociated subunits were monitored by confocal fluorescence microscopy.

A complementary DNA clone encoding the alpha subunit of the adenylate cyclase stimulatory G protein (Gs) was isolated and identified.

The two inner rings consist of seven beta subunits each, and the two outer rings consist of seven alpha subunits each.

An antibody to a peptide synthesized according to deduced amino acid sequence reacts specifically with the alpha subunit of Gs.

It contains five metal clusters of which clusters B, B ′, and a subunit - bridging, surface - exposed cluster D are cubane - type [4Fe - 4S] clusters.

Toxins that cleave three different subunits of the vesicular fusion machinery reveal the detailed kinetics of synaptic vesicle release.

Perinuclear increases in [cAMP] slowly caused the translocation of the freed catalytic subunit into the nucleus to an extent proportional to the percentage of its dissociation from the regulatory subunit.

Craig Venter «s team at the J. Craig Venter Institute in Rockville, Maryland, and San Diego, California, has made a bacterial genome from smaller DNA subunits and then transplanted the whole thing into another cell.

Molecular cloning of complementary DNA for the alpha subunit of the G protein that stimulates adenylate cyclase

Heterotrimeric guanine nucleotide - binding regulatory proteins (G proteins) dissociate into guanosine triphosphate (GTP)- bound alpha subunits and a complex of beta and gamma subunits after interaction with receptors.

Now, as Thomas Cech explains in his Perspective, atomic resolution of the structure of the large ribosomal subunit reveals that, as predicted by those convinced of a prebiotic RNA world, RNA is the catalytic component with proteins being the structural units that support and stabilize it (Ban et al., Nissen et al., Muth et al.).

Domain II of EF - P interacts with the ribosomal protein L1, which results in the largest movement of the L1 stalk that has been observed in the absence of ratcheting of the ribosomal subunits.

Concentration - dependent inhibition of adenylyl cyclases by purified Gi alpha subunits is described.

A genome consists of only four different nucleotide bases, or DNA subunits, arranged in a particular sequence.

Furthermore, NCF2, which encodes another subunit of NOX2, is associated with SLE risk in European Americans.

Suppressing the expression of even one of the many subunits making up the cap will impair the assembly of the whole cap, resulting in a proteasome - inhibitor resistant state.

Figure on the left: Analyzing the relative sensitivity of hundreds of cancer cell lines to commonly used anti-cancer drugs (each dot) reveals that cells with suppressed expression of one proteasome cap subunit are specifically resistant to treatments with the proteasome inhibitors MG132 and bortezomib.

Catalytic protein subunits of telomerase from the ciliateEuplotes aediculatus and the yeast Saccharomyces cerevisiae contain reverse transcriptase motifs.