Research from UW Medicine and collaborators indicates that a drug - like molecule can
activate innate immunity and induce genes to control infection in a range of RNA viruses, including West Nile, dengue, hepatitis C, influenza A, respiratory syncytial, Nipah, Lassa and Ebola.
The NLR family apoptosis inhibitory proteins (NAIPs) bind conserved bacterial ligands, such as the bacterial rod protein PrgJ, and recruit NLR family CARD - containing protein 4 (NLRC4) as the inflammasome adapter to
activate innate immunity.
Beutler and Hoffmann discovered receptor proteins that can recognize microorganisms and
activate innate immunity, the first step in the body's immune response.
In 2011, two scientists were awarded the 2011 Nobel Prize in Physiology or Medicine for identifying receptor proteins, named Toll - like receptors, that recognize these microorganisms and
activate innate immunity, the body's first line of defense.
Not exact matches
Platelet
activating factor receptor and
innate immunity: uptake of Gram positive bacterial cell wall into host cells and cell - specific pathophysiology.
The macrophages release cytokines that can
activate more
innate immune cells, readying them for attack on viruses or cancer cells, or they can
activate the adaptive arm of
immunity, priming it for clonal expansion.
Scientists discovered highly active beta -(1 > 3)- glucans with the ability to potentiate
innate immunity by
activating immune cells.