Sentences with phrase «adaptive mutations in»

Antibiotic Resistance, Houston, TX, USA presentation «Adaptive Mutations in LiaR are Sufficient to Confer Daptomycin Resistance in E. faecium by Inducing Phosphorylation - Independent Activation of the LiaFSR - mediated Membra...

Finally, we decompose the fitness contributions of pre-existing and de novo mutations by creating a large recombinant library of adaptive mutations in an ensemble of genetic backgrounds.

Among other findings, SWIF (r) identified several adaptive mutations in a set of genes responsible for energy and fat storage.

Not exact matches

Together, the experiment and genetics show that adaptive radiation, at least in the vial, is due «to the most basic evolutionary processes: simple mutations and natural selection.»

Until now, changes in the relative proportion of rare mutations, that could be both detrimental and adaptive, had only been shown over relatively long timescales, by comparing African and European populations.

Even after the cells were taken out of microgravity for up to 30 generations before being combined with the control strain, they maintained 72 per cent of their adaptive advantage, pointing to permanent mutations in the genes rather than merely a temporary adjustment.

«Despite the experimental data provided here, it is impossible to clearly establish whether the adaptive mutations observed were in part responsible for the extended duration of the 2013 — 16 epidemic,» they write in their paper.

They find an abundance of recent adaptive mutations etched in the human genome; even more shocking, these mutations seem to be piling up faster and ever faster, like an avalanche.

The effects of these deleterious mutations in humans and chimpanzees are probably either inconsequential or else they are compensated by adaptive changes elsewhere in the genome, Keightley says.

Bianconi I, Milani A, Cigana C, Paroni M, Levesque RC, Bertoni G, Bragonzi A. Positive signature - tagged mutagenesis in Pseudomonas aeruginosa: tracking patho - adaptive mutations promoting airways chronic infection.

To show that the technique works, the researchers validated it on a simulated dataset in which known adaptive mutations were included, as well as on canonical adaptive mutations that have been identified in human genomes through multiple molecular experiments.

These adaptive mutations can spread quickly (evolutionarily speaking) through a population in subsequent generations, a process known as a selective sweep.

SWIF (r) was shown to outperform both individual statistical techniques and other composite techniques in picking out those adaptive mutations, while producing a lower rate of false positives.

How are microbial communities assembled in the > 5,000 - y - old subsurface of marine sediment, and do they undergo adaptive evolution or accumulate mutations due to impaired DNA repair under such energy - limited conditions?