Sentences with phrase «additional human studies»

Additional human studies are planned, including one to test the drug as a preventive medicine.

Additional human studies are needed to explore how individual differences in maternal breast milk composition could predispose to intestinal inflammatory conditions, such as allergic disease.

Not exact matches

Foods produced from genetically engineered crops don't pose additional health risks to humans, a study concludes.

Additional support for the Fragile Families and Child Well - Being Study was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and a consortium of private foundations.

Recently the Journal of Human Lactation posted an article based off of a research study done to prove how birth practices do in fact effect the initial birth weight of the baby, and if the mother has had an induction, a cesarean birth, or an epidural longer then 6 hours, the additional fluids passed into her will in turn get passed into the baby, thus resulting in a «false» birth weight.

«We hope that the finding from this study will stimulate much - needed additional studies into the potential environmental hazards to human health, including the health of pregnant women.»

«This study, and specifically the concern that biomass grown and burned in polluted areas is potentially more toxic to human health, is additional evidence that human activities have consequences not yet explored and therefore not understood,» she said.

An additional study, currently available at bioRxiv, led by the researchers from the CRG and Cold Spring Harbour Laboratory, highlights the fact that a substantial part of human and mice genes have maintained an essentially constant expression throughout evolution, in tissues and various organs.

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

Professor Ali Tavassoli, who led the study with colleague Dr. Ishna Mistry, explains: «In an effort to better understand the role of HIF - 1 in cancer, and to demonstrate the potential for inhibiting this protein in cancer therapy, we engineered a human cell line with an additional genetic circuit that produces the HIF - 1 inhibiting molecule when placed in a hypoxic environment.

The research does not conclude that the Asian tiger mosquito (Aedes albopictus) can transmit Zika to humans, but it highlights the need for deeper research into additional potential vectors for the virus that has rapidly spread through the Americas since its initial outbreak in 2015, says Chelsea Smartt, Ph.D., associate professor at the Florida Medical Entomology Laboratory at the University of Florida and lead author on the study to be published this week in the Entomological Society of America's Journal of Medical Entomology.

A similar device might be ready for use in premature human babies in three to five years if additional animal tests pan out, study coauthor Alan Flake estimates.

If additional studies are successful within the next few years, MU officials will request authority from the federal government to begin human drug development (this is commonly referred to as the «investigative new drug» status).

Cucinotta said the findings show a tremendous need for additional studies focused on cosmic ray exposures to tissues that dominate human cancer risks, and that these should begin prior to long - term space missions outside the Earth's geomagnetic sphere.

«If for example we follow a new term with a gesture, we create additional input that facilitates the brain's learning,» says Katharina von Kriegstein, head of the study at the Max Planck Institute for Human Cognitive and Brain Sciences.

Dr Shanon Casperson, lead author of the study from USDA - Agricultural Research Service Grand Forks Human Nutrition Research Center, USA said: «We found that about a third of the additional calories provided by the sugar - sweetened drinks were not expended, fat metabolism was reduced, and it took less energy to metabolize the meals.

«Women ended up shouldering a lot more of the work that comes with a new baby, even though both men and women thought they added the same amount of additional work,» said Claire Kamp Dush, co-author of the study an associate professor of human sciences at The Ohio State University.

As recent data suggest, PSMA is an important cancer antigen expressed on many human prostate, bladder, renal as well as ovarian cancers, so additional study of the possible benefits of this therapy are important.»

Additional authors of the study were Kathleen R. Sullivan, social science analyst at the U.S. Department of Health and Human Services; and Katherine Kinzler, associate professor at Cornell University.

«We found hundreds of genes expressed exclusively by human astrocytes, and future studies will likely reveal additional biological differences.

The researchers stress that, because the study was conducted with mice, additional research is required before it can confirmed whether the data will apply directly to human health.

The development of methods to remove pigmentation from planarians could have significant impacts on tool development in that field, and the connection to human porphyrias makes a compelling case for additional studies of this system.

Although the current study demonstrates that loss of IL - 15Rα promotes this phenotype, future studies are needed to determine the roles of specific IL - 15Rα isoforms in muscle, as well as the associations of additional IL15RA polymorphisms in muscle phenotypes in humans.

According to one study that looked at eight fuel aridity metrics in the Western U.S. and modeled climate change's effects on them, human - caused climate change accounted for about 55 percent of the observed increases in fuel aridity between 1979 and 2015 (Figure 6), and added an estimated 4.2 million hectares of forest fire area between 1984 and 2015.7 Based on all eight metrics, the Western U.S. experienced an average of 9 additional days per year of high fire potential due to climate change between 2000 and 2015, a 50 percent increase from the baseline of 17 days per year when looking back to 1979.

The researchers caution that follow - up studies must be done over a longer period and with additional subjects before they can definitively state that re-administering gene therapy for retinal disease is safe in humans.

Together our data support the notion that targeting DGKζ, a negative regulator of T cell activation, or other regulators of Erk activation, could be useful in the treatment of human malignancy and that additional preclinical studies of intracellular «brakes» on T cell activation are warranted.

With the reference cell census data in hand, the research team is excited to conduct additional studies, including ones involving models or human patients with gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal new insights and opportunities for therapeutic development.

We can envision that DAXX can serve as a precise prognostic marker in PCa and that tissue - specific shRNA delivery targeted against DAXX can be employed in the treatment of metastatic prostate cancer in patients, in particular if we discover, through additional studies, that DAXX is a marker for lethal PCa in humans.

«Additional studies will be necessary to examine additional sodium transporters in both animal models as well as human volunteers,» said GWU's Pedro A. Jose, MD, a co-investigator in Felder's salt - related researcAdditional studies will be necessary to examine additional sodium transporters in both animal models as well as human volunteers,» said GWU's Pedro A. Jose, MD, a co-investigator in Felder's salt - related researcadditional sodium transporters in both animal models as well as human volunteers,» said GWU's Pedro A. Jose, MD, a co-investigator in Felder's salt - related research program.

However, in the spirit of the publicly - funded Human Genome Project, we believe that early release of these data may be useful to other researchers and we hope to encourage additional study.

«When we injected GMT into each of the three types of human fibroblasts, nothing happened — they never transformed — so we went back to the drawing board to look for additional genes that would help initiate the transformation,» said Gladstone Staff Scientist Ji - dong Fu, PhD, the study's lead author.

In this study, human lung cancer cells with additional copies of the opioid receptor grew more than twice as fast as tumor cells that lacked extra receptors when transplanted into mice.

Significant additional preclinical and clinical studies addressing vector transduction efficacy, biodistribution, and toxicity are required before a human in utero gene transfer protocol can proceed.

«With additional research on early - time restricted feeding on humans, we can create a more complete picture of whether this innovative method can best help prevent and treat obesity,» said Schoeller, who is a spokesperson for the Obesity Society and was not involved in the study.

However, additional studies, especially in humans, are necessary to confirm this.

But an additional 10 to 15 percent weight loss continues to cause even more improvements in measures like blood lipids and blood pressure,» says study co-author Samuel Klein, MD, director at the Center for Human Nutrition at Washington University School of Medicine.

Additional studies have found no interference with thyroid function following supplementation of human diets with isolated soy protein, and at least one study has linked soy intake to thyroid support in postmenopausal women.

However, additional animal studies, along with eventual human studies, would be required to confirm these initial findings.»

The additional two human studies were split, with one of them supporting cooling, while another lacked statistical significance to show icing's efficacy.

Two additional studies noted decreased performance with ubiquinone - 10 supplementation (a fat - soluble antioxidant) in humans after a high - intensity training program (10, 11).

Another clinical study on the bioavailability of curcuminoids investigated the effects of a patented formulation, BCM - 95 ® CG (Biocurcumax ™)-- a highly - absorbent, synergistic blend of curcumin and turmeric essential oil derived from 100 % pure turmeric (with no additional ingredients or cofactors)-- on a human volunteer group.

However, the atrogene results of the current study indicate alcohol ingestion does not exert any additional effects on ubiquitin ligase expression after exercise in human skeletal muscle.

Additional research is underway continue to confirm the initial results of this study, and provide the information to scientifically verify the benefits of the human - animal bond.

Additional studies have shown human and pet interaction helps lower blood pressure and agitation, along with providing opportunities for interaction and physical activity.

Their work has been a valuable prod to the community of scientists and policy analysts aiming to smooth the human journey, resulting in strings of additional studies.

For example, stormwater across the city of Milwaukee recently showed high human fecal pathogen levels at all 45 outflow locations, indicating widespread sewage contamination.87 One study estimated that increased storm events will lead to an increase of up to 120 % in combined sewer overflows into Lake Michigan by 2100 under a very high emissions scenario (A1FI), 57 leading to additional human health issues and beach closures.

Second, a new study was released that provides additional proof that since the late 1970s, the Earth has received much more solar energy than previously thought... that solar impact would be multiple times more powerful than the concurrent human CO2 impact.

Even If humans quickly stop polluting the atmosphere, potentially keeping a global temperature rise to well below 2 °C (3.8 °F) compared with pre-industrial times — a major goal of the Paris climate agreement — seas may still rise by an additional 9 inches to 2 feet this century, the study concluded.

This study from China provides additional proof that natural climate change is a powerful driving force that produces warning phases without human intervention.

Despite these impacts, the magnitude of additional glacier retreat has been underappreciated by scientists, policymakers and the public, says Prof Gerard Roe from the University of Washington, who led a study in 2016 that identified shrinking glaciers as «categorical evidence» of human - caused climate change.