Sentences with phrase «advancing efficacy and safety»
Organs - on - Chips Technology: A Platform for Advancing Efficacy and Safety Testing in Drug Discovery and Development
https://emulatebio.com/ Not exact matches
Because bazedoxifene has already undergone safety and efficacy studies as a treatment for osteoporosis, it may be a viable near - term option for patients with advanced breast cancer whose tumors have become resistant to other treatment options, Wardell reported.
The ADvance Trial, using a device from Functional Neuromodulation, Inc., is aimed at evaluating the safety, efficacy and tolerability of DBS in this patient population.
In particular, more work is needed to determine the safety of this therapy in advanced mouse models that can more accurately predict safety in humans, and its efficacy specifically against metastatic cancer, which is the leading cause of cancer - related deaths.
Many factors may cause differences between current expectations and actual results including unexpected safety or efficacy data observed during preclinical or clinical studies, clinical trial site activation or enrollment rates that are lower than expected, changes in expected or existing competition, changes in the regulatory environment, failure of Syndax's collaborators to support or advance collaborations or product candidates and unexpected litigation or other disputes.
Based on proof - of - concept pre-clinical studies indicating robust efficacy and favorable safety profile, the company is now advancing to conduct a clinical trial testing the efficacy of this new treatment.
A Phase I / II, Open - label, Multi-center Study of the Safety and Efficacy of IMCgp100 using the Intra-patient Escalation Dosing Regimen in Patients with Advanced Uveal Melanoma
The latest developments in CAR - T translation and manufacturing including alternate gene transfer methods to deliver CARs; novel gene editing approaches, advances in CAR design to improve safety and efficacy, and progress in creating an «off - the - shelf» allogeneic CAR - T therapy.
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial.
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo - controlled, phase 3 trial.
We carried out a multicentre single - arm phase II trial in women with AR - positive, estrogen, progesterone receptor and HER2 - negative (triple - negative) metastatic or inoperable locally advanced BC to assess the efficacy and safety of abiraterone acetate (AA) plus prednisone.
A Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01949 in Combination with Immune Therapies in Subjects with Advanced or Metastatic Malignancies
FORWARD1: A Randomized, Open Label Phase 3 Study to Evaluate the Safety and Efficacy of Mirvetuximab Soravtansine (IMGN853) Versus Investigator's Choice of Chemotherapy in Women with Folate Receptor Alpha - Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer
We pride ourselves in utilizing some of the most scientifically advanced technology, combining the best available equipment with software like EclipseTM and Radialogica that enable our clinical teams to deliver treatment with precision, safety and efficacy while capturing information and continually optimizing delivery protocols.
• Acute Binge Cocaine induces region specific effect in the straitum of BAC - D2 - EGFP mice (poster presentation at the NIDA, Washington DC, November, 2011) • Acute Binge Cocaine induces region specific effect in the straitum of BAC - D2 - EGFP mice (accepted for poster presentation at the CPDD, California, June 2011) • Lumbar Spinal Stenosis: How Much Can You Decompress Without Destabilizing the Spine (accepted for oral podium presentation at ISASS12 in Barcelona, Spain, March 2012) • Current Advances in Iliac Crest Bone Graft Alternatives for Spinal Fusion (Manuscript: The Journal of The American Academy of Orthopaedic Surgeons) • Lumbar Spinal Stenosis: How Much Can You Decompress Without Destabilizing the Spine (Manuscript: The spine journal) • Clinical Efficacy and Safety Profile of Bone Morphogenetic Protein in Spine Spine Sugery (Manuscript: European Spine Journal) • Acute Binge Cocaine induces region specific effect in the straitum of BAC - D2 - EGFP mice (Manuscript: Journal of Addictive Medicine)