Sentences with phrase «aggressive breast cancer cells»

In the study, the genetic targets were messenger RNA (mRNA) that code for certain proteins known to be biomarkers for aggressive breast cancer cells.

Not exact matches

Inflammatory breast cancer is a rare and aggressive form of breast cancer that occurs when malignant cells block the skin and lymph vessels of the...

She carried in her cells a dangerous genetic mutation and died when she was 28, after refusing surgery for her aggressive, inherited breast cancer.

«We discovered that the aggressive cancer cells that are spreading in colon, breast, and skin cancer contained a much higher portion of the protein PITPNC1, than the non-aggressive cancer cells,» says researcher Nils Halberg of the CELLNET Group at the Department of Biomedicine at UiB.

Cardiff University scientists have developed a novel anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

Extensive studies have found that 20 % to 30 % of breast cancers are characterized by over-expression of HER2, which makes the cancer cells grow and divide faster, leading to a cancer that's more aggressive and more likely to be resistant to the standard of care.

«Our data clearly suggests that AKR1B1 overexpression represents an oncogenic event that is responsible for the aggressive behaviors of basal - like breast cancer cells,» Dong explains.

«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers.»

The study, which will be published December 21 in the Journal of Cell Biology, suggests that the loss of these particular Numb proteins makes breast cancers more aggressive and resistant to chemotherapy, but points the way toward new therapeutic approaches that could improve patient outcome by preserving p53 levels.

«The research showed that the aggressive form of basal breast cancer cells may be dependent on PLK4 for survival and that depleting it induced cell death,» says Dr. Mak.

The discovery of this stem cell could explain why some breast cancers recur despite aggressive chemotherapy.

«What began with the question «what makes a particular aggressive form of breast cancer cells keep growing?»

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

A new study shows coibamide A has potent anti-cancer activity in mice and cell cultures that model brain tumors and triple negative breast cancer, two of the most aggressive and difficult - to - treat types of cancer.

For years, scientists have observed that tumor cells from certain breast cancer patients with aggressive forms of the disease contained low levels of mitochondrial DNA.

Now, University of Pennsylvania researchers have revealed how a reduction in mitochondrial DNA content leads human breast cancer cells to take on aggressive, metastatic properties.

The team's findings, published online in Nature Cell Biology, explored HIF - 1's role in triple - negative breast cancer (TNBC), an aggressive and hard - to - treat form of the disease.

The growth rate of the cells exploded, and they quickly became disorganized masses characteristic of early stage, aggressive breast cancer, the team reports in the 7 February issue of the Journal of Experimental Medicine.

Mutations in the gene increase rat susceptibility to mammary cancer and FRY reduced the growth of highly aggressive human breast cancer cells.

«Inflammatory breast cancer is a rare and very aggressive disease in which cancer cells block lymph vessels in the skin of the breast.

The signatures of the breast stem cells in the fetus were stunningly similar to the stem - like cells found in aggressive breast cancers, including a significant fraction of a virulent cancer subtype known as «triple - negative.»

A New Twist in Breast Cancer Working with mice, scientists have shown that a protein made by a gene called TWIST may be the proverbial red flag that can accurately distinguish cells that drive aggressive, metastatic breast cancer from other breast cancer Breast Cancer Working with mice, scientists have shown that a protein made by a gene called TWIST may be the proverbial red flag that can accurately distinguish cells that drive aggressive, metastatic breast cancer from other breast cancer Cancer Working with mice, scientists have shown that a protein made by a gene called TWIST may be the proverbial red flag that can accurately distinguish cells that drive aggressive, metastatic breast cancer from other breast cancer breast cancer from other breast cancer cancer from other breast cancer breast cancer cancer cells.

Low levels of a tiny RNA fragment in cells are associated with metastatic breast cancer in humans and increases the aggressive spread of breast cancer in mice, according to researchers at Whitehead Institute for Biomedical Research.

Many women are «triple negative» No one yet knows precisely why, but African - American women are roughly twice as likely as white women to have triple - negative breast cancer — so called because tumor cells in this particularly aggressive form of the disease test negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER - 2).

Inflammatory breast cancer (IBC) is an aggressive form of the disease that occurs when cancer cells enter the skin and lymph vessels of the breasts.

The breast cancer cells inhibited by the combination were of a notoriously aggressive type known as triple - negative.