Aggressive breast cancer tumors differentiated and took on cyst - like characteristics.
Not exact matches
«Study in early stage
breast cancer shows that even small
tumors can be
aggressive.»
Triple - negative
tumors are
aggressive and more likely to metastasize than other
breast cancers, and there is no effective treatment.
«By understanding how stress accelerates invasion in
aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some
aggressive breast cancers.»
The team chose to compare
breast tissue from healthy individuals with
tumor samples taken from
breast cancer patients — including both primary
tumors that had not spread from the
breast to other body sites, and highly
aggressive, metastatic
tumors.
Researchers at Washington University School of Medicine in St. Louis have discovered why
breast cancer patients with dense
breasts are more likely than others to develop
aggressive tumors that spread.
Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most
aggressive type of skin
cancer, as well as
breast cancer and neuroblastoma, a
tumor that typically affects patients aged 15 or younger.
It has been recognized that the more
aggressive triple - negative
breast cancer occurs more frequently in African American women, but no previous study has examined racial differences in
tumor genotype and how they might contribute to the risk of
cancer recurrence.
«In addition to having a higher prevalence of triple - negative
breast cancers than Caucasian women — something that has been documented in previous studies — we found that African American women with
breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the
cancer had a significantly higher prevalence of the TP53 driver mutation, basal
tumor subtype and greater genomic diversity within
tumors, all of which suggest more
aggressive tumor biology,» says Tanya Keenan, MD, of the MGH
Cancer Center, lead author of the
Cancer Center, lead author of the study.
The results suggest that the pockets of stiffer extracellular matrix in the
breasts of obese women contribute to
tumor growth as well as to more
aggressive cancers, Fischbach says: «People always think it's all about soluble factors, chemicals.
A new study shows coibamide A has potent anti-
cancer activity in mice and cell cultures that model brain
tumors and triple negative
breast cancer, two of the most
aggressive and difficult - to - treat types of
cancer.
For years, scientists have observed that
tumor cells from certain
breast cancer patients with
aggressive forms of the disease contained low levels of mitochondrial DNA.
«What we see over and over in trying to treat some of the most
aggressive and intractable
cancers, including many lung, brain, ovarian,
breast, melanoma and sarcoma
tumors, is that the
tumor fights back.
The researchers found that non-Hispanic white women were more likely to have smaller
tumors, and more likely to have the less -
aggressive HR + / HER2 - subtype of
breast cancer, compared with African - American women, who were more likely to have large
tumors, more likely to have the
aggressive triple - negative
breast cancer, and 40 to 70 percent more likely to be diagnosed at stage 4 of all subtypes of
breast cancer.
The
aggressive basal - type
breast cancers often metastasize, seeding new
tumors in distant parts of the body.
Scientists exploit gene therapy to shrink
tumors in mice with an
aggressive form of
breast cancer.
Many women are «triple negative» No one yet knows precisely why, but African - American women are roughly twice as likely as white women to have triple - negative
breast cancer — so called because
tumor cells in this particularly
aggressive form of the disease test negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER - 2).
«We found a strong reduction in the risk of estrogen - receptor - negative [ER --RSB-
breast cancer in particular, which is exciting because that type of
tumor, while rarer than estrogen - receptor - positive [ER +]
tumors, tends to be
aggressive.»
THURSDAY, May 3, 2018 (HealthDay News)-- Much of the debate over when to start having mammograms has focused on lives saved, but new research suggests that early screening might also translate into smaller
tumors and less
aggressive breast cancer treatments.
May 16, 2018 • An
aggressive type of
breast cancer — a HER2 - positive
tumor — often shrinks with Herceptin treatment, but side effects can be tough.