Our provocative findings in
Aging Cell mean that it's time to re-think the notion that taking away ovaries has no significant downside to a dog's healthy longevity.
Not exact matches
In the case of neural
cells, it
means that imprinted methylation is dynamically shaping the adult brain over time and could play a role in
aging.
Eye diseases — such as
age - related macular degeneration, as well as a genetic condition called Stargardt's macular dystrophy that afflicts young people — are considered excellent candidates for stem
cell therapy because the eye is an immune - privileged site,
meaning transplanted
cells are not as likely to be rejected as foreign compared with transplants elsewhere.
Recent studies suggest that the total loss in brain volume due to atrophy — a wasting away of tissue caused by
cell degeneration — between our teen years and old
age is 15 percent or more, which
means that by the time we're in our seventies, our brains have shrunk to the size they were when we were between 2 and 3 years old.
Then there's the West Palm Beach symposium, held to recruit participants for a study testing what happens when
aging people get infusions of plasma (the fluid part of blood packed with signaling proteins and other molecules but no red or white
cells) from young people who've taken a drug
meant to activate their immune system.
Oxidation is also a primary
means by which the body kills invaders, such as viruses and bacteria, or removes
aging or sick
cells.
Scientists at King's College London have found that people who have previously suffered from acne are likely to have longer telomeres (the protective repeated nucleotides found at the end of chromosomes) in their white blood
cells,
meaning their
cells could be better protected against
aging.
As we
age, the nitric oxide
meant to cause dilation is increasingly destroyed by reactive oxygen species such as superoxide, which are produced by many components of our body's own
cells, including organelles called mitochondria.
Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free longer, but not above human MLSP of around 122 years; thus these therapies do not affect epigenetic
aging whatsoever, they are degenerative
aging problems not regular healthy
aging problem (except OncoSENS - only when you Already Have Cancer - which cancer increases epigenetic
aging, but cancer removal thus does not change anything / makes no difference about what happens in the other
cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
cells / about what happens in the normal epigenetic «
aging» course in Normal non-cancerous healthy
cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
cells) Although there is not such thing as «healthy
aging» all
aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not affect their quality of life (enough yet), that is «healthy
aging»: ApoptoSENS - Clearing Senescent
Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent
cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp / means longer LongTerm Potentiation - means longer brain function means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their age), and both are correlated to M
cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the brain is causal to how long we live; keeping brain amyloid - free and keeping our memories / neuron sharp /
means longer LongTerm Potentiation -
means longer brain function
means longer heavy brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger brain for their
age), and both are correlated to MLSP).
Sure enough, when the researchers examined the brains of PD patients, they found more
cells exhibiting signs of senescence than in people without the disease — and especially astrocytes, as they had expected.7 This was true even after matching patients for
age,
meaning that PD subjects had even more senescent astrocytes in their SNcs than is typical for people their
age (ranging in this case from 50 — 92 years at autopsy)-- and remember,
aging already drives an increase in the burden of these
cells as compared with young people, even in those who have yet to develop Parkinson's disease.7
Here we consider two surface markers thought to define these
cells in mice, CD8 and Killer
cell lectin - like receptor G1 (KLRG1), and a
means we developed to remove these
cells from the blood of
aged C57BL / 6 mice.
Here we investigate
age - related
mean and variance changes in gene expression measured by RNA - seq of fat, skin, whole blood and derived lymphoblastoid
cell lines (LCLs) expression from 855 adult female twins.
Retinol rejuvenates skin
cells and increases collagen production, which
means brighter, softer, younger - looking skin that's more protected from the damage that comes with
ageing.
Antioxidants are beneficial for health because they neutralize disease - causing misfits called free - radicals in our bodies, which are essentially unstable molecules missing an electron who will stop at nothing to find one, even if it
means stealing it from healthy
cells and thereby causing chain reactions of illness and
aging.
As we
age, the rate of skin
cell turnover slows,
meaning the body takes longer to shed old skin
cells and generate new ones.
Telomere length is arguably the best marker of biological
age, and shorter
mean telomere length, usually measured in your white blood
cells, is associated with increased risk of heart disease, obesity, cancer, stroke, dementia, and premature death (2).
Just as the number on the bathroom scale isn't always a simple reflection of calories consumed vs. calories burned, the number of years you've lived isn't always a reflection of your biological
age (
meaning the
age of your
cells).
Over 1 million people live out here and high traffic volume
means attitudes flaring, cuss words being shared kindly with the windows down, and drivers of all
ages on the
cell phone texting and taking selfies while driving which
means traffic violations and more traffic tickets.