While drugs such as acetylcysteine are capable of breaking the disulphide bonds that are partially responsible for the particularly viscid nature of airway mucus, in practice, aerosolized acetlycysteine is irritating to
airway epithelium and can promote significant bronchoconstriction.
In addition, some of the genes associated with airway mucosal response are strongly involved with
airway epithelium repair and regeneration.
Enhanced Expression of Myristoylated Alanine — Rich C Kinase Substrate (MARCKS) in
Airway Epithelium of an Animal Model of Allergic Airway Inflammation and Human Patients with COPD
Here we present a novel human Airway Lung - Chip containing a fully - differentiated human mucociliary
airway epithelium separated from a pulmonary microvascular endothelium by a semi-permeable membrane that allows for immune cell infiltration.
J. K. Watson, S. Rulands, A. C. Wilkinson, A. Wuidart, M. Ousset, A. Van Keymeulen, B. Göttgens, C. Blanpain, B. D. Simons, E. L. Rawlins Clonal dynamics reveal two distinct populations of basal cells in slow turnover
airway epithelium Cell Reports, 12 (1), 90 — 101 (2015)
In immunocompromised individuals (chemotherapy patients, for example) or poorly controlled diabetics, upper airway Aspergillus infections can invade the mucosa and underlying tissue and become lethal, so it is particularly critical to understand its interactions with
the airway epithelium.
When Liesman infected human airway cells in the lab with this re-engineered virus, she saw infected cells ball up and puff out of
the airway epithelium.
While the PIV - infected epithelial cells retained their natural elongated, columnar shape, the same cells infected with RSV balled up and puffed out of
the airway epithelium, causing the infected cells to accumulate in the lumen of the airway.
Not exact matches
«This is a whole new way of looking at immune surveillance in the
epithelium of the human gut and
airway,» said Lo, a distinguished professor in the medical school's Division of Biomedical Sciences.
A research team from the University of Minnesota and the Mayo Clinic took cells from the lining (
epithelium) of human
airways and exposed them to Alternaria.
Role of IL - 17A, IL - 17F, and the IL - 17 receptor in regulating growth - related oncogene - α and granulocyte colony - stimulating factor in bronchial
epithelium: implications for
airway inflammation in cystic fibrosis.
The higher scores (> 3) in some groups related primarily to the fact that virus infection had induced inflammatory infiltrates and epithelial cell necrosis with desquamation of the
epithelium and collection of cellular debris in
airways of these animals.
contain immunoprotective respiratory
epithelium, the tissue lining the respiratory tract, which moistens and protects the
airway and functions as a barrier to potential pathogens and foreign particles;