Sentences with phrase «altered microenvironment»

«Altered microenvironment promotes progression of pre-invasive breast cancer: myoepithelial expression of integrin DCIS identifies high - risk patients and predicts recurrence» by Michael D Allen et al. published in Clinical Cancer Research on Tuesday 3 December.

In cancer, the protein helps malignant tumors evade the immune system as they metastasize and alter their microenvironment in a stealth type of expansion.

Not exact matches

One team of researchers from Vanderbilt University aims to unlock how irradiation might alter the mechanical properties of the microenvironment.

Now, Salk scientists have pinned down how signals from this microenvironment encourage pancreatic tumors to grow by altering their metabolism.

The new study took the next logical step: Can the tumor microenvironment be altered so that it promotes or thwarts metastasis?

Masters et al. discuss the often overlooked contribution of the stromal microenvironment as an extrinsic factor to immunosenescence and inflammation.12 Accumulation of senescent stromal cells which demonstrate the senescent associated secretory phenotype (SAPS), may alter tissue structure and function, and increase local inflammation.13 The impact of altered lymphoid stromal microenvironment may be widespread and include altered haematopoiesis, reduced lymphatic flow and disrupted secondary lymphoid organisation, which consequently will alter antigen transportation and presentation to T cells.12

Two other neoadjuvants, doxorubicin and cyclophosphamide, also promoted metastasis by altering the tumor microenvironment.

Altered stromal microenvironments in non-lymphoid organs may also impact immune function.

Does nanotechnology offer unique opportunities to alter or influence the tumor microenvironment to suppress progression and invasion?

The result is an accumulation of senescent cells, which causes inflammation, tissue degradation and the production of growth factors that alter the tissue microenvironment, leading to disease.

Generation of a Th2 microenvironment through interleukin - 13 (IL - 13) stimulation induced features of asthmatic airways and induced vascular wall activation through increased expression of E - and P - Selectin, but did not alter rhinovirus growth.

Cancer cells use altered metabolic pathways to sustain rapid growth and to overcome enormous stress encountered in tumor microenvironment.

Colonic insult impairs lymph flow, increases cellular content of the lymph, alters local lymphatic microenvironment, and leads to sustained inflammation in the rat ileum.