Sentences with phrase «although autologous»

Although autologous cell transplantation circumvents the need for immunosuppressive treatment, it is not always available or most effective.

Although an autologous tier 2 NAb response is not sufficient for vaccine protection against HIV - 1, it may be a necessary step in various strategies intended to induce bNAbs.

Not exact matches

Although many immunosuppressive strategies have failed, the recent use of autologous hematopoietic stem and progenitor cell (HSPC) transplantation has shown therapeutic promise.

A similar pattern of neutralization activity for the GL VHH was seen, with GL B9 and A14 neutralizing R2 only and GL B21 neutralizing both autologous viruses (Fig. 7C, D) although in all cases the neutralization by the GL VHH was less potent than by the mature VHH.

Additionally, genetic modification or pre-conditioning of autologous cells to boost the levels of VEGF [4], ANG [5], and TGF -[6], all previously linked to alleviation of ALS symptoms, could potentially lead to an augmented response, although this must first be assessed in animal models, such as the SOD1 mice.

Autologous bone marrow mesenchymal stromal cells (BM - MSCs) secrete factors known to improve neurological function, and clinical trials have shown BM - MSC transplantation to be safe and feasible [2], although results have been variable.

Although regulatory precedents have been set for various autologous and allogeneic products in the United States, Asia, and the European Union, regulatory guidance continues to evolve for a widening array of cell products.

Although complicated, surgical procedures such as the autologous transplantation of peripheral RPE to the macular region [63]--[66] and macular translocation, where the neural retina is detached and the fovea relocated to a less diseased area of RPE [67]--[69], have been shown to stabilize visual acuity in AMD patients.