Sentences with phrase «although autologous cell»

Although autologous cell transplantation circumvents the need for immunosuppressive treatment, it is not always available or most effective.

Not exact matches

Although many immunosuppressive strategies have failed, the recent use of autologous hematopoietic stem and progenitor cell (HSPC) transplantation has shown therapeutic promise.

Additionally, genetic modification or pre-conditioning of autologous cells to boost the levels of VEGF [4], ANG [5], and TGF -[6], all previously linked to alleviation of ALS symptoms, could potentially lead to an augmented response, although this must first be assessed in animal models, such as the SOD1 mice.

Autologous bone marrow mesenchymal stromal cells (BM - MSCs) secrete factors known to improve neurological function, and clinical trials have shown BM - MSC transplantation to be safe and feasible [2], although results have been variable.

Although regulatory precedents have been set for various autologous and allogeneic products in the United States, Asia, and the European Union, regulatory guidance continues to evolve for a widening array of cell products.