Not exact matches
In addition, delayed identification increases the risk of long - term problems such as
early dementia, depression, more rapid aging of the
brain, or of the devastating degenerative neurological condition known as chronic traumatic encephalopathy or CTE (
although medical science has not come close to quantifying that risk).
Although amyloid clogs the
brain early on, memory loss tracks much better with a different protein, tau, which forms so - called «tangles» within nerve cells.
Several compounds that boost glutamate signalling in the
brain have reached
early clinical trials,
although it is too soon to say if they will pass the larger trials needed to prove their worth.
Although why, exactly, excessive
brain growth is related to autism remains a mystery, the new work helps to confirm that signs of the disorder appear
early — knowledge that could lead to detection and treatments, such as behavior therapy, at a younger age.
It is produced by the
brain and spinal cord into
early adulthood as it is needed for many developmental processes, and
although earlier studies of human white matter hinted at its involvement in skill learning, this is the first time it has been confirmed experimentally.
Professor Geoff Pilkington, study co-author and Head of the
Brain Tumour Research Centre, said: «Although this work is still at an early stage, we have demonstrated key elements that are associated with tumour cell binding to blood vessels and this may provide a target for future drug development to prevent the development of secondary tumours in the b
Brain Tumour Research Centre, said: «
Although this work is still at an
early stage, we have demonstrated key elements that are associated with tumour cell binding to blood vessels and this may provide a target for future drug development to prevent the development of secondary tumours in the
brainbrain.
Although meat eating helped to shape the evolution of human
brains, behavior and toolmaking, our
early ancestors seem to have been better scavengers than hunters
Although H. naledi's cranium is shaped like that of H. erectus, its
brain size is that of an
earlier australopith, and tiny for its 5 - foot - tall body.
Although variations in the NPAS1 and NPAS3 genes have been linked to
brain disorders including autism, they aren't obvious drug targets because their function is most important in
early life.
The idea is that inhibiting Aβ formation to reduce growth of Aβ - based plaques in the
brains of Alzheimer's patients may be therapeutic,
although it isn't yet clear how
early in the disease process such an intervention would need to be employed to be effective.
«These results suggest that phytoestrogens can interfere with the normal estrogen feedback mechanisms with respect to release of gonadotropin in the ewe...
although most studies into the effects of phytoestrogens have concentrated on changes in the reproductive tract, there are indications that they interfere with the hormone balance between the ovaries and the hypothalamo - adenohypophysical system... ewes on phytoestrogens have shown follicular abnormalities such as numerous small follicles, deficient antrum formation and signs of
early atresia... it is possible that the permanent changes brought about by phytoestrogens in the
brain are a result of these compounds interacting with estrogen receptors in this tissue, and subsequently influencing the re-synthesis or replenishment of cyto - plasmic estrogen receptors... phytoestrogens can interfere with the delicate feedback mechanisms involved in the release of the gonadotrophins.»
Although Chloe survived and flourished through so many difficult times, she was not able to survive the
brain tumor which took her mind, and ultimately her life,
earlier this year.
Although a great deal of synaptic plasticity occurs during
early childhood as the
brain is developing, plasticity in the form of learning and memory continues to shape our synapses throughout our lives.
The noncommunicable diseases associated with
early childhood adversity have garnered a great deal of attention recently, as they are predicted to account for 90 % of the morbidity seen in high - income countries by the year 2030.62
Although this has prompted some to focus on the automatic
brain processes that perpetuate the associated unhealthy lifestyles, 63 relatively little attention has been given to preventing or mitigating the toxic stress that allows these automatic processes and unhealthy behaviors to be learned and adopted in the first place.
Although negative
early life relational experiences have the ability to shape the child's developing
brain, relationships can also be protective and reparative.
For example, prenatal maternal anxiety is associated with an altered function of the placenta, in a way that may allow more cortisol to pass from mother to fetus.8 This probably underlies some of the alterations in fetal and child
brain neurodevelopment following
early exposure to stress and may also be one of the mediators of an altered epigenetic profile,
although many other biological systems, including serotonin, dopamine and the pro-inflammatory cytokines, are also likely to be involved.