Sentences with phrase «although gene loss»

We identified human X-linked genes whose gametologs have been pseudogenized or completely lost from the Y chromosome and inferred which evolutionary forces may be acting to retain genes on the Y. Although gene loss appears to be largely correlated with the suppression of recombination, we observe that X-linked genes with functional Y homologs evolve under stronger purifying selection and are expressed at higher levels than X-linked genes with nonfunctional Y homologs.

Not exact matches

Although there are several ways to remove RB from the cellular machinery, the group found that complete loss, rather than inactivation, of the RB gene was associated with changes in gene - networks closely linked to aggressive disease.

Although DNA gain and loss in human occurred mostly in different regions, they both tended to impact on the same biological processes, while in mouse DNA loss was enriched for developmental genes and DNA gain did not associate with any particular biological process.

Although persistent loss of IGF - 1R expression ultimately induced cell stasis and death, both of these processes are regulated by the tumor suppressor gene p53 that is commonly mutated in human prostate cancers.

Although pigment - related hearing loss can occur in any breed, two genes that cause this type of deafness are more commonly found in certain breeds, such as Great Dane, Collie, Old English and Shetland Sheepdogs, Samoyed, Dalmatian and Bull Terriers, according to Louisiana State University veterinarian Dr. George M. Strain.