Although gene regulation is complex and we still have a lot to learn, scientists do know of three ways in which our genes are turned off and on.
Not exact matches
Although the
regulation of this
gene has a strong «cell cycle control» component, I was more interested in studying cell cycle
regulation «proper.»
«
Although we know that ZMYND11 controls RNA polymerase II travel ratio in the
gene body, we still don't know how this protein, which does not physically interact with polymerase II, actually achieves this
regulation,» Shi said.
The results suggest that,
although the lack of light chain synthesis can be due to a lack of
gene rearrangement, there may also be transcriptional
regulation, which may also be important for the expression of light chain immunoglobulins in immature B cells.
Although the biological mechanisms through which this polymorphism could affect aging are not known, it is adjacent to two
genes called CDKN2A and CDKN2B, which play an important role in cell cycle
regulation.
Although a smaller set of
genes was affected, regular meditators showed post-intervention differences in a
gene network characterized by lower
regulation of protein synthesis and viral genome activity.
Once again, the
genes that are subject to HAR2
regulation are still unclear,
although GBX2, a transcription factor that controls proper expression of
genes involved in embryo morphogenesis, is one promising candidate.
Although there is complex
regulation across the CYP4F
gene cluster, the opposing effects between the two SNPs in the CYP4F
gene cluster appear to compensate for each other and their effect on warfarin dose requirement is unlikely to be clinically significant.
Although the mechanism of age - related decline in DNA repair capacity is unknown, growing evidence suggests that epigenetic events (e.g., DNA methylation) contribute to the ageing process and may be functionally important through the
regulation of the expression of DNA repair
genes.
Although scientists and laypeople alike once believed that the effects of
genes on health and behavior are direct and immutable, scientists now recognize that there is substantial
regulation of genetic expression by the environment, resulting in
gene — environment interactions.