Sentences with phrase «animal testing studies»

It was hard for me to believe that you can find me an expert in Animal Testing Studies.

Animal tests studies of PBDEs have revealed the potential for damaging the developing brain and the reproductive system.

Not exact matches

The lengthy research cited on HVMN's website and others are primarily animal studies, rather than human studies, and primarily test one of two compounds in combination, rather than the half - dozen contained in a product like SPRINT.

All the animals completed a series of cognitive tests at the start of the study and were injected with a substance that allows scientists to track changes in their brain structures.

A 2010 test - tube and animal study found that sorghum possesses significant anti-inflammatory properties due to its high content of these plant compounds (5).

Created when sap is boiled down into maple syrup, Quebecol is a novel phenolic compound that has yet to be tested for bioactivity in animal or human studies.

An in - vivo (inside the body) study was undertaken, with animals being given identified samples of coconut oil and their blood tested.

so often they just look at potential markers — but those don't always equate to diseases)- what was the health of the those being studied - I'm assuming the test subjects were people, but other studies done on animal subjects might not be as reliable as those done on humans.

«We are constantly on the look out for findings from animal studies that could be tested in human babies.

Studies show that these models can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.

Forward - thinking scientists, many with funding from PETA and its international affiliates, are developing methods for studying diseases and testing products that don't require the use of animals and are actually relevant to human health.

In animal studies, the Magnamosis device consistently created anastomoses that were comparable or better than hand - sewn or stapled alternatives as demonstrated in tissue samples and tests of the strength of the connection.

The researchers caution that the booster therapy used in their new study will not be available on the market or even for use in human trials anytime soon; it must await years of animal testing for safety and effectiveness first.

In medicine today, physician - scientists and basic scientists supplement support for their research by applying their expertise part time to develop and test commercial products.1 In my own field, vision science, university - based researchers obtain additional funding through clinical and electrophysiologic studies, pathology, imaging, biochemistry, and animal model development performed for pharmaceutical and instrument companies.

Mitchell guesses that there will probably be 10 more years of rigorous testing in animals before moving on to human clinical studies.

In subsequent studies the researchers plan to analyze further relevant datasets in order to test different scenarios of the evolution of the earliest animal phyla.

The study wasn't about designing a new way of testing animal behavior, either; the same test has been used in rodents.

Moreover, getting a better picture of what the virus looks like and understanding its properties through animal testing and studying patients» blood might help vaccine developers pinpoint specific issues, says Pei - Yong Shi, a virologist at The University of Texas Medical Branch at Galveston.

Still used today by some companies, the test involves applying a small amount of the substance under study to an animal's eye or skin for several hours, and then observing whether or not irritation occurs over the following week or two.

It had never been tested in people, only in two animal studies from the 1940s.

Nath's team is currently developing an animal model of Nodding syndrome to further study the disease and test potential therapies.

And a recent study in Regulatory Toxicology and Pharmacology (vol 64, p 345) shows that animal tests missed 81 per cent of the serious side effects of 43 drugs that went on to harm patients.

Holzschuh went looking for research on this topic and found only 22 studies that tested how rock climbing might affect plants or animals.

New tests based on human biology can predict many adverse reactions that animal tests fail to do, and could, for example, have detected the risk signals produced by Vioxx, which in animal studies appeared to be safe, and even beneficial to the heart.

Drugs that disrupt the enzyme, his animal studies suggest, could prevent Alzheimer's with less risk of unwanted side effects — an approach that he expects to begin testing in human trials within three years.

The deficient animals, for example, gave up more easily in a classic forced swimming test, were less inclined to explore, and were more inclined to stay near the wall of a cage, «a widely accepted index of anxiety,» the researchers noted in their study.

The results are published in the scientific journal Food & Nutrition in the article: Meals based on vegetable protein sources (beans and peas) are more satiating than meals based on animal protein sources (veal and pork)-- a randomized cross-over meal test study.

In the new study, Professor Pisani and colleagues used cutting edge statistical techniques (Posterior Predictive Analyses) to test whether the evolutionary models routinely used in phylogenetics can adequately describe the genomic datasets used to study early animal evolution.

And by providing an animal model for the fetal damage, the studies should also ease the path for testing potential vaccines and treatments.

In the new study, Ji's group put SHANK3 - deficient mice through a battery of sensory tests, finding that the animals had lower sensitivity than normal mice to heat and heat - related pain — akin to the soreness a person feels after a sunburn.

But vaccines that only contained HIV's surface protein looked lackluster in animal and test tube studies, and then proved worthless in large - scale clinical trials.

The study is one of the first to test if the «landscape of fear» model, a scientific theory that has been used to explain how animals move and interact with the environment based on their fear of being attacked by their predators, is applicable to large open marine systems involving wide - ranging species, like sharks and turtles.

Shea notes that although he and his colleagues have yet to finalize their measurements on how well their nanoparticles bind to various PLA2 molecules, their test - tube results suggest that they could have a similar high affinity for PLA2s as their previous nanoparticles had for melittin, the bee venom protein that stopped the toxin in animal studies.

«Most pain medications that have been tested in the past decade have failed in phase II human trials despite performing well in animal models,» notes Clifford Woolf, MD, PhD, director of Boston Children's F.M. Kirby Neurobiology Center and a co-senior investigator on the study with Michael Costigan, PhD.

While most research studies begin in test tubes, cells grown in the laboratory and animal models before moving to humans, the opposite is true here.

However, Laksari and Kurt emphasize that their findings are predictions that need to be tested more extensively in the lab, either with animal brains or human brains that have been donated for scientific study.

A similar device might be ready for use in premature human babies in three to five years if additional animal tests pan out, study coauthor Alan Flake estimates.

A new study published in Annals of Botany shows that plants react to anesthetics similarly to the way animals and humans do, suggesting plants are ideal objects for testing anesthetics actions in future.

To explore the function of the animals» trilling calls in the new study, the researchers tested the ability of human listeners to detect subtle differences in synthetic calls.

«Now that we know the mice can be vulnerable to Zika infection, we can use the animals to test vaccines and therapeutics — and some of those studies are already underway — as well as to understand the pathogenesis of the virus,» said senior author Michael Diamond, MD, PhD, a professor of medicine at Washington University.

Our studies have improved our understanding of the basic biology underlying MMA, created a novel animal model for testing interventions and, now, led us to the promise of a new therapy.»

«Given the key similarities to human infections, a marmoset model of Zika may be useful for testing of new drug and vaccines,» said Texas Biomedical Research Institute virologist Jean Patterson, Ph.D. «Having an animal model of Zika infection to study may help us identify places where we might be able to block transmission.»

Blue 1: According to CSPI: «One (unpublished) animal test suggested a small cancer risk, and a test - tube study indicated the dye might affect neurons.

The current study found that harmine re-creates roughly the same amount of beta cell division, both in cell and animal tests.

«These platforms will, hopefully, in the future, be used as an animal alternative during pre-clinical testing to more accurately direct these studies toward successful results in humans.»»

Ko is quick to note that these new findings do not warrant radical dietary changes in people with Crohn's: More studies, including more refined genetic analyses of fatty acids and Crohn's and testing in animal models, are needed.

The results need be tested and confirmed in animal studies before researchers can be sure that HtrA1 is the link between ApoE4 and Alzheimer's in humans.

He and colleagues tested the concept in an animal model of apnea, publishing their findings in the journal SLEEP in 2002 and launched a subsequent pilot study in humans in 2007.

Yong, a neuroscientist, initially had the idea to test the acne medicine in an animal model since minocycline has many anti-inflammatory properties that he thought could be useful in treating MS. Soon after obtaining successful research results, in studies also supported by the MS Society of Canada and MSSRF, Yong teamed up with Metz who led the transition into a pilot clinical trial, then a Phase 2, and finally the definitive Phase 3 trial.

«Our work and that of our colleagues on stress and CRF have been mechanistically implicated in Alzheimer's disease, but agents that impact CRF signaling have not been carefully tested for therapeutic efficacy or long - term safety in animal models,» said the study's principal investigator and corresponding author Robert Rissman, PhD, assistant professor in the Department of Neurosciences and Biomarker Core Director for the Alzheimer's Disease Cooperative Study (Astudy's principal investigator and corresponding author Robert Rissman, PhD, assistant professor in the Department of Neurosciences and Biomarker Core Director for the Alzheimer's Disease Cooperative Study (AStudy (ADCS).