Sentences with phrase «animal rodent models»

Animal rodent models are useful tools for studying obesity as they will readily gain weight when fed high - fat diets.

Not exact matches

Using gene editing to create rodents that are ideal research models could narrow the genetic divide between humans and their animal stand - ins.

p11 is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue from depressed patients.

«The project's goal is to accelerate the development of technologies for mapping the brain's circuitry in animal models, specifically in the marmoset monkey, whose neural circuits are much closer to human compared with rodent models, and to connect the results to the diagnosis and treatment of human neurological disorders and mental illness.»

Harding also argues that because rodent studies suggest that these animals do lose neurons to alcohol, they may be unreliable models for the human hippocampus.

Unlike rodent models, which are developed from inbred strains of mice kept in controlled environments, companion animals, like humans, are genetically diverse and are exposed to many of the same environmental influences as their owners are.

A lot of the work that we do relies on the use of rodents, animal models, rats and mice in particular.

For the JCI study, the team applied the radiotracer to monitor olfactory sensory neuron population dynamics in a rodent model, using PET to measure its uptake across the animals» lifespan, including during age - related neurodegeneration.

Studies in typical model animals — mice — are rarely illuminating, because the rodents often still behave normally when researchers manipulate genes that should cause these disorders.

Also, research in other animal models, such as rodents, has shown anesthesia exposure early in life can lead to cell death in the brain and cognitive impairments.

Pandey performed the experiments using an animal model during which rodents were exposed to alcohol for a long period of time.

- CRISPR / Cas9 in Rodents Animals: The good, The bad and the ugly: March 30th - CRISPR / Cas9 has revolutionized the creation of complex mouse and rat models.

General Product Information Obesity - High Fat Diets for Diet - Induced Obesity Models Metabolic Syndrome - Diet - Induced Metabolic Syndrome in Rodent Models Diabetes - High Fructose / Sucrose Diets for inducing Hypertriglyceridemia and Insulin Resistance in Rodents Atherosclerosis - Diet - Induced Atherosclerosis / Hypercholesterolemia in Rodent Models Hypertension - Phenotypic Expression of Hypertension in Rodent Models through Dietary Manipulation NAFLD (Non-alcoholic Fatty Liver Disease) Cancer - Creating a Clean Background for Oncology Research Test Compounds / Kaolin Pellets Diet and Immunology Focus: Arsenic in Grain - Based Laboratory Animal Diets and Effects on the Rodent Toxicological Phenotype Focus: The Importance of a Proper Control Diet

Diet - Induced Metabolic Syndrome in Rodent Models Animal Lab News - March 2007 Angela M. Gajda, MS, Michael A. Pellizzon, Ph.D., Matthew R. Ricci, Ph.D. and Edward A. Ulman, Ph.D..

Dosing Animals Via Diet Measuring Food and Water Intake in Rats and Mice Laboratory Animals - A Critical Part of In Vivo Research Diet - Induced Metabolic Syndrome in Rodent Models

There has been a growing body of literature using rodents as models of human obesity, even though there are many confounding factors including species, strain, age of the animals, type of diet, level of fat, and type of control diet.

Diet - Induced Metabolic Syndrome in Rodent Models - An article from the March 2007 issue of Animal Lab News on how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models, authored by our scienRodent Models - An article from the March 2007 issue of Animal Lab News on how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models, authored by our scienModels - An article from the March 2007 issue of Animal Lab News on how diets made from purified ingredients influence the phenotypes of the MS in commonly used rodent models, authored by our scienrodent models, authored by our scienmodels, authored by our scientists.

To address these different topics we are developing relevant animal models that will be used in combination with primary neuronal cultures, rodent brain slices, and brain tissues.

Due to the capacities of the 15 partner centers, CELPHEDIA covers 3 big families of animal models: non mammalians, rodents and non-human primates.

More importantly, in vivo inhibition of intestinal and lung inflammation rodent models suggests effectiveness to resolve inflammation with low toxicity to the animals.

We selected mice as the rodent species with which to prove this concept as they are a major agricultural, health and conservation pest, they are the most sophisticated animal model, and this knowledge base can be leveraged, and naturally occurring genetic elements known in mice but not other species can be exploited.

While an animal model of depression may seem like an absurd idea, currently, lipopolysaccharide (LPS), an endotoxin produced by gram - negative bacteria, is used to induce these clinical models in rodents.

Also noted by IER studies are an increase in the expression levels of silent mating type information regulation 2 homolog 1 (SIRT1), an NAD + - dependent deacetylase.20 The expression of SIRT1, also increased by prolonged ER in rodents, is linked to the up - regulation of cellular stress resistance and improved outcomes in animal models of metabolic, neurodegenerative and inflammatory diseases.106, 107These findings have been suggestively accompanied by improvements in resilience to disease progression in rodent models of Type 1 diabetic nephropathy 20, survival following induced ischaemic injury 21 and a reduction in oxidative stress.105

Rodent Models: Interventional IER trials in animal populations have exclusively used rodent mRodent Models: Interventional IER trials in animal populations have exclusively used rodent mModels: Interventional IER trials in animal populations have exclusively used rodent mrodent modelsmodels.

Three animal studies from Allen Taylor and his colleagues at Tufts University compared the effects of resistant starch versus highly digestible starch on eye health in rodent models.

Generally, Lascelles notes, companion animal disease models better reflect the complex genetic, environmental and physiological influences in human diseases, as opposed to the traditional rodent models.