Sentences with phrase «animal toxicity studies»

Not exact matches

At present, there have been no studies on allergenicity and toxicity of Golden Rice, which should be first established in animal feeding trials before feeding trials on humans commence.

Note that toxicity studies of medication usually require treatment with huge doses over periods of time involving most or all of the animal's lifetime.

The pharmacologist felt the animal studies submitted were not a good indication of possible toxicity in humans, since animals absorb thalidomide poorly.

However, animal studies also showed clear toxicity with certain administration regimes.

This tumor - targeted action of isoprenoids was manifested in animal studies showing no toxicity of isoprenoids at tumor - suppressive doses (reviewed by Mo & Elson, Exp Biol Med, 2004, 229:567 - 85).

But overall, the resulting toxicity of the wastewater due to its silver content was negligible to zebrafish embryos — a model animal used in toxicity studies.

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

Determination of toxicity and side effects; first studies on animals (rodents and nonrodents) that may lead to the leading structure.

Production of some compounds in this family of environmentally persistent chemicals — associated with liver toxicity, reduced fertility and a variety of other health problems in studies of people and animals — has been phased out in the United States and many other nations.

«If there are ways other than animal studies to get results — in vitro models of toxicity being one of them — we should pursue them,» he said.

Animal studies have not found any toxicity issues with using CBD.

This past Thursday marked the one - year anniversary of The Curious Case of Campbell's Rats, wherein we took a wild ride through over two decades of animal research in which Dr. T. Colin Campbell of China Study fame showed that dietary protein, whether it comes from animals or plants, protects against aflatoxin toxicity and the initiation of new precancerous lesions while simultaneously promoting the growth of precancerous lesions that have already formed.

In animal studies, Lactobacillus rhamnosus has been found to reduce the intestinal absorption and toxicity of organophosphate insecticides.

Other studies of animals indicated the cardiotoxicity, renal toxicity or hematological toxicity of erucic acid as well (3, 4).

Though there are no reports of vitamin D toxicity in humans, based on animal studies, it would take 176,000,000 IU of vitamin D to kill a 110 pound person or she would need to be taking approximately 40,000 IU daily over time.

Further testing is being pursued After passing chronic and acute toxicity testing in animals, a pilot study was undertaken with HCV patients.

Animal studies have identified reproductive toxicity as the most sensitive effects of boron ingestion.

While little data about toxicity exists, lab animal studies have shown toxicity to the nervous system and liver at high doses.

Safety considerations in the design and interpretation of clinical trials indicates that «some animal studies have suggested the potential for dose - dependent fetal toxicities (for example, growth impairment, skeletal malformations and cardiovascular anomalies) associated with excess Vitamin D supplementation.

Dr. Eric Dunayer of the ASPCA Animal Poison Control Center (APCC), board certified by the American Board of Toxicology, Inc. (DABT) and having a special interest in xylitol toxicosis, specifically states in a risk assessment paper written about C.E.T. AQUADENT Drinking Water Additive: Based on published studies of xylitol toxicity in dogs and the APCC's experience, proper use of this product (according to label directions) should not present a risk of hypoglycemia in dogs.

The EPA's Companion Animal Studies guidelines are insufficient to predict the toxicity of spot - on products.

All of the animalEO products would fall into the category of «These products have not been evaluated for use with pregnant or breeding animals» - as we have not done scientific studies to prove toxicity or safety of the individual products.

Concerns about the possible health effects of PDBEs arose in the late 1990s, and studies have reported that PDBEs cause liver and nerve toxicity in animals.

I would also point out that while the carcinogenic quality of dioxins have been well established in animal studies, there is much uncertainty regarding the dose / response relationship as to just * how * toxic they are and to what degree, if at all, the toxicity bio-accumulates.