Over the past 10 years the number of overdose deaths from prescription painkillers — also known
as opioid analgesics — has tripled, from 4,000 people in 1999 to more than 15,000 people every year in the U.S. today.
Mitragynine / Corynantheidine Pseudoindoxyls
As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β ‐ Arrestin ‐ 2.
Not exact matches
Analgesic use included nonsteroidal anti-inflammatory drugs (NSAIDs, such
as naproxen) in 38 percent of patients,
opioids (morphine and related drugs) in 16 percent, and other non-opioid
analgesics in 12 percent.
Most clinical guidelines currently recommend NSAIDs
as the second line
analgesics after paracetamol, with
opioids coming at third choice.
The body also synthesizes endogenous
opioids, known
as endorphins, which bind to the same receptors and have the same
analgesic effects
as morphine.
Painkillers are generally broken down into three categories:
opioid (narcotic)
analgesics, non-narcotic
analgesics (which include NSAIDs), and adjuvant therapies such
as anticonvulsants, muscle relaxants, and antidepressants.
For surgeries
as well
as for acute and chronic conditions we use all our available and safe resources, including
opioids, local anesthetics, NSAIDs (non-steroidal medications) and oral and injectable
analgesics for the complete comfort of your pet.