Sentences with phrase «as abnormal cells»

Not exact matches

Non-alcoholic fatty liver disease (NAFLD) is defined medically as macrovesicular steatosis, or abnormal retention of lipids (fats) sufficient and large enough to distort or replace the nuclei of liver cells among those who consume less than 20 grams -LRB-.7 ounces) of alcohol per day.

In the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autism.

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

Breast pseudolumps are not cancerous, nor are they a collection of abnormal but benign cells (such as in a fibroadenoma.

The team's key discovery was that stem cells lacking an enzyme responsible for pseudouridine modification of RNA, known as PUS7, produce abnormal amounts of protein.

Cytology - based screening, known as the Pap test or Pap smear, is used to detect abnormal cells.

Treating the mice with antibodies against CD4 + T - cells four weeks after experimental heart attacks — to deplete that subset of T - cells — prevented the progressive abnormal enlargement of the left ventricle that leads to heart failure, as compared with untreated mice.

Of particular interest are the emerging techniques for genomics and proteomics, which allow profiles of gene expression and protein synthesis to be produced and comparisons to be made between normal and abnormal cells, as well as between cells before and after exposure to medicines or toxic chemicals.

But it's much harder to develop therapies that restore malfunctioning genes that should be triggering cell death in abnormal cells, known as tumor - suppressor genes.

Abnormal and uncontrolled production of this class of proteins, known as transcription factors, allow for cells to bypass growth control mechanisms and to develop characteristics necessary for invading surrounding tissues.

«The findings provide new insight into how cells faithfully transmit this organizational information as embryos develop, and into what goes wrong when cellular development goes awry, thereby giving rise to abnormal cell development and diseases such as cancer,» says senior study investigator Danny Reinberg, PhD, professor of biochemistry and molecular pharmacology at NYU Langone and a Howard Hughes Medical Institute investigator.

Other diseases, such as the rare lung disease LAM, also involve circulating abnormal cells, Langer says.

As with most cancers, triple - negative breast cancer (TNBC) cells have abnormal amounts of chromosomes or DNA copy number aberrations (CNAs) in their genomes.

Now, results of a new study by Johns Hopkins Kimmel Cancer Center scientists suggests a powerful role for the protein in normal breast cells, acting as a tumor suppressor that halts abnormal cell growth.

Researchers are studying how NK cells recognize cancer cells as abnormal and how other cells, known as regulatory T cells, can command NK cells to hold their fire, in order to prevent them from attacking the body's own tissues.

«The genome of these cancer cells is less abnormal as compared to cancers caused by tobacco and alcohol, where there are even more mutations present,» he says.

Consistent with that possibility, fused cells often exhibited the same abnormal growth characteristics as cancer cells.

It is believed to result from a combination of genetics and environmental factors such as irritants and allergens that drive T lymphocytes to produce factors that cause abnormal changes in keratinocytes, the predominant cell type in the outermost layer of skin, as well as changes in other cells in the underlying dermis.

It's thought that the high pressure observed in tumors is a result of these abnormal blood vessels, which leak fluid and proteins into the area between tumor cells, known as the interstitial space.

Vitiligo occurs when the body is triggered to look at melanocytes, cells which give color to the skin, as foreign or abnormal.

The abnormal white blood cells — known as B cells — sometimes released skeins of DNA similar to NETs.

The presence of these abnormal circuits may also inhibit the natural process of removal of unnecessary developing brain cells known as pruning.

Using patient - derived stem cells known as induced pluripotent stem cells (iPSC) to study the genetic lung / liver disease called alpha - 1 antitrypsin (AAT) deficiency, researchers have for the first time created a disease signature that may help explain how abnormal protein leads to liver disease.

For more than 100 years, researchers have been unable to explain why cancer cells contain abnormal numbers of chromosomes, a phenomenon known as aneuploidy.

Immune cells also recognize cancer cells as abnormal, but such cells have the ability to turn off immune responses.

«If centrioles aren't there to aid proper chromosome segregation, p53 acts as backup to prevent making abnormal cells.

Thomas Look and colleagues use a type of genomic screen and identify abnormal HGF expression as a crucial factor for development of a class of acute leukemia in leukemia cell lines and clinical samples.

As cells grow and multiply, by chance there can be uneven distribution of normal vs. abnormal DNA to different cells.

Antibody dependant cellular cytotoxicity (ADCC)- When antibodies coat an HIV - infected cell identifying it as something abnormal that needs to be killed.

Only by understanding the behavior of normal cells, she maintained, would scientists learn how to prevent abnormal behaviors, such as cancer.

As seen in Figure 2, the abnormal BM cells were found to exhibit eccentric, large, round - to - oval / convoluted nuclei with mostly fine chromatin and prominent nucleoli and moderate - to - abundant gray cytoplasm with several cells exhibiting multiple diminutive cytoplasmic vacuoles.

This disease occurs when abnormal immune cells known as histiocytes grow and divide nonstop, often killing healthy cells nearby.

Our ambition is to interlink complementary biological and computational expertise so as to drive the generation of new knowledge on the characteristics of normal and abnormal stem cells.

Abnormal cells in the early embryo are not necessarily a sign that a baby will be born with a birth defect such as Down's syndrome, suggests new research carried out in mice at the University of Cambridge.

Senescent cells began their existence skin cells, or as related cells that normally play supporting roles in other organs, but were forced into an abnormal state where they lost the ability to divide and reproduce themselves as a protective response to some danger.

«In fact, abnormal cells with numerical and / or structural anomalies of chromosomes have been observed in as many as 80 - 90 % of human early stage embryos following in vitro fertilization,» says Professor Thierry Voet from the Wellcome Trust Sanger Institute, UK, and the University of Leuven, Belgium, another senior author of this paper, «and CSV tests may expose some degree of these abnormalities.»

At the time, a CVS test found that as many as a quarter of the cells in the placenta that joined her and her developing baby were abnormal: could the developing baby also have abnormal cells?

The glands lining the inner wall of the colon are the sites for most abnormal cell behavior such as uncontrolled cell growth, which results in polyps (non-cancerous growths) and later on in adenocarcinomas or tumors.

Understanding the conditions that cause these cells to go off to different fates may have a bearing on health problems such as ectopic pregnancy, which occurs when the embryo develops outside of the womb in about 1 of 60 pregnancies, or molar pregnancy, which is abnormal tissue growth within the uterus that affects about 1 in every 1,000 pregnancies.

The relatively small number of such cells in a youthful tissue is so small as to be harmless, but after decades of accumulation, the number becomes large enough that their abnormal metabolic state begins to pose a threat to surrounding, healthy tissues.

«Over recent years, major investments in research in areas like immunology, cell biology and genetics have provided impressive insights into the basic biology of fundamental processes, such as injury, repair and neoplasia (abnormal cancerous tissue growth),» Elias said.

The dementia in the other half appeared to have been caused by abnormal protein deposits (known as Lewy bodies), stroke - related tissue death (microinfarcts), cell damage, or some combination thereof.

SOOTHING FACIAL MASK: Keep your skin soft, smooth and blemish - free with natural sodium bentonite clay which draws abnormal shedding of dead skin cells and excess bacteria as it dries.

As it progresses, there I an abnormal increase in the white blood cells and this type of cancer is often diagnosed in older people while this is rare for people below age 45.

Abnormal Krebs cycle and / or oxidative phosphorylation cause (s) not only glucose hypometabolism but also the increased generation of reactive oxygen species (ROS), oxidative damage, and programmed cell death such as apoptosis.

This catabolic process helps the body rid itself of intracellar pathogens as well as abnormal cancer cell development.

Foods and compounds which pro-apoptotic, as their name tend to indicate, are the natural process which the body takes advantage of by utilising it to discard any unnecessary and abnormal cells.

Doctor will first administer an aesthesia before using a curette to scour away the infected skin cells and then use a needle or a loop that is electrically heated to stop the bleeding as well as damage the remaining abnormal cells.

External factors such as ultraviolet radiation (UV) and toxins also damage skin cells, leading to redness, discoloration, yellowing, abnormal growth, and poor texture.