Consequently, the lab expanded, and found more and more data about
Asgard archaea and many other exciting lineages.
For my project, I work on a new group within
the Asgard archaea, known as the Freyarchaeota, where I use bioinformatics tools to unveil their possible complexity and what makes them unique.
By doing so, I help increase our understanding of the diversity within
the Asgard archaea and their evolutionary relation to the eukaryotic domain.
Recently, this very lab described
the Asgard Archaea, an archaeal phylum with clear signs of cellular complexity, such as the presence of eukaryotic membrane trafficking components.
In an international collaboration, the Ettema - lab has published a new paper in Nature about a group of archaea that gives unique insight into the evolution of cellular complexity,
the Asgard archaea.
Importantly, the composite genomes of
Asgard archaea encode homologs of actin genes, actin - binding proteins, multiple ESCRT complex homologues, and tubulin.
«We found that
Asgard archaea share many genes uniquely with eukaryotes, including several genes that are involved in the formation of structures that give eukaryotic cells their complex character.
Studying
Asgard archaea in more detail represents a prioritized goal for Thijs Ettema and his research group.
In this weeks» edition of Nature, researchers from Uppsala University in Sweden, along with collaborators from the USA, Japan, Denmark and New Zealand report the discovery of a new group of Archaea,
the Asgard archaea, which reveal important details on how eukaryotic cells evolved their complexity.
Last, the investigation of informational processing and cellular machineries have revealed that genomes of
Asgard archaea, which affiliate with eukaryotes in the tree of life (see the figure), encode proteins that they only share with eukaryotes.
Eukaryotes (gray branch) are suggested to have emerged from
the Asgard archaea upon endosymbiosis with an alphaproteobacterial partner (the mitochondrial endosymbiont).
Not exact matches
Now,
Archaea include at least four major supergroups, the Euryarchaeota and the TACK, Asgard, and DPANN archaea, all of which comprise several different, potentially phylum - rank clades (see the f
Archaea include at least four major supergroups, the Euryarchaeota and the TACK,
Asgard, and DPANN
archaea, all of which comprise several different, potentially phylum - rank clades (see the f
archaea, all of which comprise several different, potentially phylum - rank clades (see the figure).
While this view has been changing for some time, a revolution in our thinking came with the discovery of Lokiarchaeum («Loki») and other members of the «
Asgard» clade of
archaea through metagenomic sampling of ocean sediments in 2015.
With the discovery of
Asgard» clade
archaea, the homologs of key eukaryote cytoskeletal proteins have, for the first time, been identified in
archaea.